Following subcutaneous dosing, the apparent clearance (CL/F) of enoxaparin is approximately 15 mL/min. Metabolism Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency. Renal clearance of act...
For treatment of acute ST-segment elevation myocardial infarction in geriatric patients ≥75 years of age, do not use an initial intravenous bolus. Initiate dosing with 0.75 mg/kg subcutaneously every 12 hours (maximum 75 mg for the first two doses only, followed by 0.75 mg/kg dosing for th...
Metabolized by liver via desulfation and/or depolymerization to lower molecular weight species Elimination Half-life: 4.5 hr (single dose based on anti-Xa activity); 7 hr (repeated dosing) Total body clearance: 26 mL/min Excretion: Urine (40%) ...
Modified dosing for patients with severe renal impairment (CrCl <30 mL/min) across all indications Elderly patients Low-weight patients Patient self-injection videoIf your patients are going home with Lovenox self-injectables, this video provides helpful instructions. ...