Oxidation Resistance 1(OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant pathways, cell cycle, neuronal protection, and arginine methylation. In 2019, five patients...
Oxidative stress, caused by reactive oxygen species (ROS), including superoxide (O2−), hydrogen peroxide (H2O2), and hydroxyl radical (OH), is one of the unavoidable crises for the vast majority of aerobic organisms by damaging biomolecules such as lipids, proteins and DNA1. ROS (H2O2 in...
Reduction-oxidation (redox) plays a critical role in NF-kappaB activation. Diverse stimuli appear to utilize reactive oxygen species (e.g. hydrogen peroxid... Jin, D.-Y.,HZ Chae,SG Rhee,... - 《Journal of Biological Chemistry》 被引量: 1301发表: 1997年 The dual functions of thiol-based...
The dietary consumption of cuprizone – a copper chelator – has long been known to induce demyelination of specific brain structures and is widely used as model of multiple sclerosis. Despite the extensive use of cuprizone, the mechanism by which it ind
(Guo et al.2010). In the same study, impaired activation of ATM by either DNA damage or oxidation both resulted in the accumulation of aggregated protein species. Additional oxidative stress further exacerbated protein aggregation only in the latter. This indicates that a loss of ATM can ...
100 °C and 110 °C, respectively, and helium and hydrogen were used as the carrier and burning gases, respectively. To calculate methane flux, the rate of change in methane concentration per unit surface area of the chamber within a specified time interval was calculated using the followi...
mice shortly after weaning were mainly naïve (Fig.1b). However, even at this young age we noticed a significant reduction ofTet2/3DKO naïve CD4 cells and an increase of the activated CD44+CD62L+ as well as CD44+CD62L− cells, reflecting the acquisition of activation (Fig.1b, c...
Peroxisomal ACOX1 (acyl‐CoA oxidase 1) is the first and rate‐limiting enzyme in fatty acid β‐oxidation of VLCFA and a major producer of hydrogen peroxide (H2O2) (Schrader and Fahimi, 2006). ACOX1 deficiency (OMIM #264470) in humans is an autosomal recessive disorder that causes a rapid...
Ni/SiO2 catalyst effective for methane decomposition into hydrogen and carbon nanofiber. J. Catal. 217, 79–87 (2003). CAS Google Scholar Liu, X. et al. Structural changes of Au–Cu bimetallic catalysts in CO oxidation: in situ XRD, EPR, XANES, and FT-IR characterizations. J. Catal. ...
Rancourt DG, Mercier PHJ, Cherniak DJ, Desgreniers S, Kodama H, Robert JL, Murad E (2001) Mechanisms and crystal chemistry of oxidation in annite: resolving the hydrogen-loss and vacancy reactions. Clay Clay Miner 49: 455-491Rancourt, D.G., Mercier, P.H.J., Cherniak, D.J., Des...