Losartan's prevention of angiotensin II binding causes vascular smooth muscle relaxation, lowering blood pressure.Angiotensin II would otherwise bind to the AT receptor and induce vasoconstriction, raising blood pressure. 吸收 Losartan is approximately 33% orally bioavailable. Losartan has a T of 1 ...
Baseline pre-dialysis blood pressure among standard-arm patients was 167.5 mmHg (SD ± 18.2), which at the end of the 12-month follow-up was reduced to 162.4 mmHg (SD ± 10.2), giving a difference of 5.1 mmHg. This drop in pre-dialysis systolic blood pressure was sta...
Both hypertension and epilepsy are frequent chronic illnesses, with increased blood pressure greatly raising the risk of epilepsy due to its relationship with cerebrovascular disease, doubling the risk when compared to people with normal blood pressure. Objective: The effect on pharmacokinetics and ...