Losartan's prevention of angiotensin II binding causes vascular smooth muscle relaxation, lowering blood pressure.Angiotensin II would otherwise bind to the AT receptor and induce vasoconstriction, raising blood pressure. 吸收 Losartan is approximately 33% orally bioavailable. Losartan has a T of 1 ...
In turn, intradialytic hypotension is associated with mortality29,30, thereby raising questions regarding the recommended post-dialysis blood-pressure target range. Similarly, studies indicate a U-shaped or reverse J-shaped relationship between systolic blood pressure and mortality among ESRD patients31,...
Biopsies showed an active chronic inflamma- tory cell infiltrate in the lamina propria together with focal acute cryptitis and a granulomatous response around dam- aged crypts raising the possibility of Crohn's disease (Figs. 1 and 2). We were reluctant to accept the diagnosis of Crohn's dis...