We’re sorry, something doesn't seem to be working properly. Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.Summary Abstract Losartan/hydrochlorothiazide (HCTZ) [Hyzaar®] is a fixed-dose combination of the angiotensin II receptor ...
Thus, a working hypothesis for the binding pocket in AT1R for the ligand AT II would be a positively charged site, a lipophilic pocket or pockets, and a hydrogen bond acceptor.203 The first leads to a nonpeptidic structure that demonstrated AT1R inhibition were three microbial metabolites (103...
the medications used in addition to the initial 25–50 mg dose of losartan were prescribed at the discretion of participating physicians. We did not set a specific target BP or rules for additional drugs