H12.5, hydrochlorothiazide 12.5 mg; L50; losartan 50 mg; L100, losartan 100 mg The solid line shows time course of mean blood pressure in subjects who received L50/H12.5 in the double-blind (DB) period and L100/H12.5 in the extension period. The dotted line shows time course of mean ...
controlled hypertension, receiving stable therapy with lisinopril (an angiotensin-converting enzyme inhibitor) or losartan (an angiotensin II receptor blocker).This was a phase IV double-blind, placebo-controlled trial conducted from August 2008 to March 2010 (ClinicalTrials.gov identifier: NCT00734630)...