dosage, form, labeller, route of administration, and marketing period. Access now Product Images PreviousNext International/Other Brands Almazine (Psyco Remedies) / Anxiedin (U-Liang) / Idalprem (Novartis) / Lorabenz / Lorsilan (Belupo) / Somagerol / Temesta (Wyeth) / Wypax (Wyeth KK)...
Alternatives to the Intravenous Route of Administration Intravenouslorazepamis the current first-line treatment forSE, but requiring intravenous access is a major disadvantage. Most episodes of SE start in an out-of-hospital setting and, even when medical help is available, obtaining intravenous access...
administration (even though the i.v. dose of lorazepam was 1 2 the intranasal dose). Although both drugs are absorbed following intranasal application, this route of administration would appear to have limited potential for the acute treatment of seizures....
Plasma lorazepam concentrations were also determined, and for each occupancy method, the concentration required to produce 50% occupancy (EC(50)) was calculated because this parameter is independent of the route of lorazepam administration. For the in vivo binding assay, lorazepam was dosed orally (...
Lorazepam tablets are administered orally. For optimal results, dose, frequency of administration, and duration of therapy should be individualized according to patient response. To facilitate this, 0.5 mg, 1 mg, and 2 mg tablets are available. ...
Pharmacokinetic Optimisation of Benzodiazepine Therapy for Acute Seizures According to the route of administration, the efficacy was 28.6 to 100% (intrarectal) and 54 to 100% (intravenous) for diazepam, 82 to 100% (intravenous) for lorazepam, and 79% (intranasal), 93 to 100% (intramuscular) ...
of sedation and muscle relaxation in patients undergoing assisted ventilation. Acute episodes of severe anxiety or panic also are effectively treated by lorazepam, particularly by the parenteral route. The most widespread use of lorazepam is in the treatment of ambulatory individuals with neurotic ...
Route of Administration ORAL DEA Schedule CIV Active Ingredient/Active Moiety Ingredient NameBasis of StrengthStrength LORAZEPAM (UNII: O26FZP769L) (LORAZEPAM - UNII:O26FZP769L) LORAZEPAM 0.5 mg Inactive Ingredients Ingredient NameStrength SODIUM LAURYL SULFATE (UNII: 368GB5141J) MAGNESIUM STEAR...
The incidence varied from one study to another, depending on the dosage, route of administration, use of other central-nervous-system depressants, and the investigator's opinion concerning the degree and duration of desired sedation. Excessive sleepiness and drowsiness were the most common consequences...
Overall, this study demonstrated favorable pharmacokinetics of intranasal lorazepam in relation to standard administration methods. Intranasal delivery could provide an alternative, noninvasive delivery route for lorazepam.doi:10.1177/009127000104101106Daniel Paul H. Wermeling...