The article begins by providing an overview of the conceptual roots of addiction as a disorder as described in DSM-5 and ICD-11. The underlying organ-pathological perspective is then criticized and an alternative social-science perspective is presented: The "dependence syndrome" defines addiction ...
and was summarizedseveral years ago in this blog. I first wrote about methylation as a cause of aging inthis space in 2013. For here and now, I’ll just add that we have direct evidence for changes of type (1). Inflammatory cytokines are up-regulated with age. Apoptosis is up...
Amplification of the DNA was performed in a PCR reaction mix consisting of approximately 2 ng/µL of template DNA, forward and reverse primers (10 pmol/µL), 5× HOT FIREPol® Blend Master Mix (Solis BioDyne, Tartu, Estonia), and molecular grade water added up to 20 µL. The ...