Long-term tolerability of tramadol LP, a once-daily formulation, in patients with osteoarthritis or low back pain. J Clin Pharm Therap. 2005;30:113–20.H. Malonne, M. Coffiner, D. Fontaine, B. Sonet, A. Sereno, and A. Peretz. Long-term tolerability of tramadol LP, a once-daily ...
The effects of concomitant use or discontinuation of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with traMADol are complex. Use of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with traMADol hydrochloride requires careful consideration of the effects on the parent drug, traMADol, and...
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The effects of concomitant use or discontinuation of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with traMADol are complex. Use of CYP3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with traMADol hydrochloride requires careful consideration of the effects on the parent drug, traMADol, and...
For the treatment of PD, drug therapy with levodopa or dopamine agonists is the first choice [1]. However, the development of motor complications such as wearing-off and dyskinesias due to long-term treatment has been an issue in the treatment of PD [2,3]. Drugs with different mechanisms...
published results for the primary outcome measure (hip function at 12 months postoperatively). We use a simulation study to illustrate how this model also has more general application for conventional short ordinal scores, to select amongst competing models of varying complexity for the cut-point ...
It is conceivable that the earlier reported association between gender and long-term pain may have been a consequence of the fact that more women were in the higher age strata [47]. Also, among the 85 PHN subjects, who have been enrolled in the present study, there were...
Long-term use of narcotic/antidepressant medication in the management of phantom limb pain. Pain. 1986;24:191–6. Article CAS PubMed Google Scholar Wang G, Weng Y, Ishiguro Y, Sakamoto H, Morita S. The effect of tramadol on serum cytokine response in patients undergoing pulmonary lobectomy...
Anyone considering the use of venlafaxine hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond...
Background: Gastric electrical stimulation (GES) therapy is indicated for the treatment of drug-refractory gastroparesis (GP). However, the long-term effects of GES therapy on GP symptom control and identification of the optimal parameters to activate this long-term efficacy have not been investigate...