Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; there was a reduction in ...
In long-term, open label schizophrenia studies with aripiprazole (the active ingredient contained in Abilify MyCite) lauroxil, 14% of patients with HbA1c less than 5.7% at baseline developed levels of 5.7% or higher post-baseline. Undesirable alterations in lipids have been observed in patients ...
Important changes in gut microbiota at the end of treatment remained at follow-up, including significant increases in bacterial diversity and relative abundances of Bifidobacteria and Prevotella. Our observations demonstrate the long-term safety and efficacy of MTT as a potential therapy to treat ...
AIMS: This study assessed the long-term safety, tolerability, and maintenance of the therapeutic effect of aripiprazole once-monthly 400 mg (AOM 400) in patients with schizophrenia. METHODS: This 52-week, open-label study included patients previously enrolled in 1 of 2 AOM 400 randomized ...
It offers a high-level view on the current state of long acting drugs technologies and services market and its likely evolution in the mid-long term. A general overview of long acting drugs delivery and the different types of long acting drugs delivery systems. Additionally, it highlights the ...
“If someone thinks that they will do better on a long acting, or they just want a long acting, it's fine to use it first-line,” Ehret said during the APhA session. “At our academic medical center, we try to get everyone on LAIs because the adherence is better...
Patients randomized to AM received intradeltoid or intragluteal injections of 400 mg/month Abilify Maintena (aripiprazole once monthly, Otsuka, Tokyo, Japan) at baseline and 10–20 mg/day oral aripiprazole for 2 weeks. Thereafter, they received 400 mg/month im AM in their del- toid or ...
Drowsiness occurred with initial treatment and usually subsided with continued use or lowering of the dose. Extrapyramidal symptoms (EPS) may occur in susceptible patients, but is usually reversible with appropriate therapy; EPS symptoms include akathisia. ...