Depression is a common problem amongst older people. It gives rise to considerable suffering and disability and, even after successful treatment, it frequently recurs. The range of causes of depression in older people is more diverse than in younger adu...P, Wilkinson...
Reid S, Barbui C: Long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants. BMJ 2010, 340:752-756.Reid S, Barbui C. Long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants. BMJ 2010; 340: c1468....
Relapse prevention must be carried on over 4-6 months, in many cases maintenance therapy has to be continued for years if not lifelong. Treatment strategies include antidepressants, lithium and anticonvulsants for all of which efficacy in long-term treatment of depression has been shown. In this...
To date, research into the effects of antidepressant treatments for individuals withmajor depressionhas only concentrated on short-term outcomes says Colman, and that there is limited knowledge about long-term results. However, it's important to note that it's unlikely that the effects are just t...
memorylearning strategymemory impairmentDifferences in Subjective Organisation of Verbal Memory and Learning in Brain-Damaged Adolescents. Objective: Subjective organization (SO) of verbal memory and learning was investigated for 44 adolescent patients. Method: The patients were subdivided into four clinical ...
LTD，即Long-Term Depression的缩写，直译为“长期抑郁症”。这个术语在医学领域中广泛使用，代表着一种持续时间较长的精神健康问题。在英语中，它的流行度为127，表明它在专业交流中较为常见。在神经科学中，LTD和LTP（长时程增强）是学习和记忆机制的重要组成部分，它们反映了神经元之间的可塑性变化。
treatment-resistant depression are highly susceptible to recurrent depressive episodes, the ability of DBS to support long-term maintenance of an antidepressant response and prevention of relapse is a treatment advance that can mean the difference between getting on with your life or always looking ...
rst line treatment. Long term pharmacotherapy of depression. Tricyclic antidepressants should not be first line treatment.Long term pharmacotherapy of depression. Tricyclic antidepressants should not be first line treatment.EBSCO_AspBmj British Medical Journal...
长时程抑制（LTD）是突触可塑性的重要形式，与学习记忆紧密相关。近十年的研究揭示了LTD的分子机制及其在进化上的高度保守性。LTD的诱导和维持涉及到多种关键分子，包括细胞膜受体、细胞信号转导通路、基因表达的调控因子。LTD的分子机制主要通过以下三个关键步骤实现：首先，爬行纤维的激活导致浦肯野细胞...