However, there is a paucity of data on the potential side effects of long-term statin use over many decades. Comprehensive risk assessment, including calculation of life-time ASCVD risk, as well as incorporating non-traditional risk factors including lipoprotein (a), strong family history of ...
Increased plasma levels of low-density lipoprotein cholesterol (LDL-C) are causally associated with atherosclerotic cardiovascular disease (ASCVD), and statins that lower LDL-C have been the cornerstone of ASCVD prevention for decades. However, guideline-recommended LDL-C targets are not achieved in ...
What are the side effects of statins? Do statins help treat COVID-19? Further information Altoprevside effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. ...
26. Sinzinger H, Wolfram R, Peskar BA (2002) "Muscular side effects of statins." J Cardiovasc Pharmacol, 40, p. 163-71 27. Itakura H, Vaughn D, Haller DG, O'Dwyer PJ (2003) "Rhabdomyolysis from cytochrome p-450 interaction of ketoconazole and simvastatin in prostate cancer." J Urol...
What are the long-term effects of statin therapy? is significantly reduced when patients' LDL cholesterol levels are substantially lowered using statin therapy, uncertainties about the overall effect of statins ... Bays,Harold - 《Nature Clinical Practice Cardiovascular Medicine》 被引量: 4发表: 2006...
This study aimed to assess the long-term effects of tofogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes lacking an apparent history of cardiovascular disease. Methods This was a prospective obse...
Therefore, medications for obesity treatment must be viewed through the lens of long-term use when evaluating their safety and efficacy. A lesson from the withdrawal of previous antiobesity drugs is that uncommon but serious adverse effects may become apparent only when a drug is used in larger ...
Statins are known to cause skeletal muscle side effects, but it is currently unclear if they also affect cardiac muscle. Control mice underwent either atorvastatin (Ator), pravastatin (Prava) (both 5mg/kg/day) or vehicle (Veh) treatment for up to 6.5 months. After two months, Ator and Pr...
What The Experts Say About The Side Effects Of Statins. What Are They? What Causes Them? Who Is Most At Risk? How Are They Treated? Is Your Ab Workout Hurting Your Back? Dr. Stuart McGill Advises to Trade in the Crunch for the Bird Dog, Side Bridge, & Stir the Pot ...
9. Downs JR, Clearfield M, Tyroler HA, Whitney EJ, Kruyer W, Langendorfer A, Zagrebelsky V, Weis S, Shapiro DR, Beere PA, Gotto (2001) "Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS): Additional perspectives on tolerability of long-term treatment with lovastati...