Common(1% to 10%): Injection site reactions (including pain, thrombophlebitis), thrombophlebitis with IV administration, phlebitis, transient pain at injection site Frequency not reported: Pain at IM injection site[Ref] Immunologic Common(1% to 10%): Jarisch-Herxheimer reaction[Ref] ...
Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening, and emergence of suicidal thoughts and behaviors. Venlafaxine hydrochloride is not approved for use in...
Uncommon (0.1% to 1%): Neutropenia, blood creatine phosphokinase increased, alanine aminotransferase increased, aspartate aminotransferase increased, platelet count decreased, blood creatinine increased, blood potassium decreased, deep thrombophlebitis Rare (less than 0.1%): White blood cell count decreased...
An increased risk of hip fracture has been reported in a cohort study. The risk was significantly increased among patients prescribed long-term high PPIs.[Ref] Endocrine Common (1% to 10%): Increased serum gastrin Very rare (less than 0.01%): Gynecomastia Frequency not reported: Decreased/...
certain patients during the early phases of treatment. An increased risk of suicidal thinking and behavior in children, adolescents, and young adults (aged 18 to 24 years) with major depressive disorder (MDD) and other psychiatric disorders has been reported with short-term use of antidepressant ...
In 2 longer-term trials, the mean change in blood glucose from baseline in patients treated with this drug (mean exposure 213 days; n=646) was 5 mg/dL (vs. placebo -0.05 mg/dL). Among patients with major depressive disorder receiving the extended-release formulation of this drug, a FBG...
An increased risk of suicidal thinking and behavior in children, adolescents, and young adults (aged 18 to 24 years) with major depressive disorder (MDD) and other psychiatric disorders has been reported with short-term use of antidepressant drugs....
Paroxetine mesylate is not approved for use in pediatric patients. Oral route (tablet; tablet, extended release; suspension) Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients in short-term studies. ...