Clinical trials, Randomized controlled trials, Long-term follow-up, Non-compliance, Treatment switching, Co-intervention, Loss to follow-upRandomised trials with long-term follow-up can provide estimates of the long-term effects of health interventions. However, analysis of long-term outcomes in ...
McFarland, H.F.; Reingold, S.C. 2005:The future of multiple sclerosis therapies: redesigning multiple sclerosis clinical trials in a new therapeutic eraMultiple Sclerosis 11(6): 669-676 Esiri;, M. 2000:Benign multiple sclerosis? Clinical course, long term follow up, and assessment of prognos...
long-term followupcoagulationliver function testPMM2-CDG is the most common congenital disorder of glycosylation (CDG), which presents with either a neurologic or multisystem phenotype. Little is known about the longitudinal evolution.We performed data analysis on PMM2-CDG patients' clinical features ...
Long-term outcomes after bariatric surgery: fifteen-year follow-up of adjustable gastric banding and a systematic review of the bariatric surgical literature. Ann Surg. 2013;257(1):87-94.PubMedGoogle ScholarCrossref 43. Fleisher LA, Beckman JA, Brown KA, et al; American College of ...
data monitoringdecision rulesWhen the data from a long-term clinical trial are reviewed continually over time for evidence of adverse or beneficial treatment effects, the classical significance tests are not appropriate. A simulation procedure is described which provides the correct critical regions ...
Wunderink et al conduct a long-term follow-up evaluation of a randomized clinical trial comparing maintenance treatment with dose
The incidence of ISR (binary restenosis rate) for BMSs was found to be between 20 and 30%, based on medium- and long-term follow-ups of clinical trials (Iqbal et al. 2013). DESs are associated with a significantly reduced rate of ISR (% diameter stenosis (DS)) compared to BMSs. For...
Purpose: Delineation of the long-term follow-up data on a series of patients with malignant mesothelioma, who received a single intrapleural dose of a nonreplicative adenoviral (Ad) vector encoding the herpes simplex virus thymidine kinase "suicide gene" (Ad.HSVtk) in combination with systemic ga...
Long-term follow-up also suggested that appropriate and active salvage treatment has a survival benefit for some patients, and late cardiopulmonary toxicities should be noticed during follow-up. Trial registration The trial was registered at https://clinicaltrials.gov (ClinicalTrials.gov Identifier: ...
1 fashion to Optilume BPH or Sham (100 Optilume BPH; 48 Sham). Long-term measures include International Prostate Symptom Score (IPSS), peak urinary flow rate (Qmax), Post-Void Residual Urine (PVR), quality of life measures and sexual function. Follow-up beyond one year was limited to ...