"The long-term success of this treatment confirms the remarkable success we've seen since the very first Gleevec trials," said Druker, director of the OHSU Knight Cancer Institute, a Howard Hughes Medical Institute Investigator and JELD-WEN Chair of Leukemia Research in the OHSU School of Medici...
When originally approved under the accelerated approval program, the long-term benefits of this second-line drug therapy in refractory CML could only be assumed. However, follow-up studies of the patients enrolled in the research studies have shown that 95 percent of those with refractory disease ...
Serious side effects of Sprycel Along with its needed effects, dasatinib (the active ingredient contained in Sprycel) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. ...
Some side effects of nilotinib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects...
For example, variability was noted in patients with chronic myeloid leukemia (CML), and the level of molecular response achieved with imatinib (Gleevec) therapy suggesting variability exists in the patient’s therapy adherence. A strong correlation between adherence rates of ≤ 90% or > 90% and ...
The leukemia-specific AML1/ETO fusion gene has been shown to be detected by reverse transcriptase polymerase chain reaction (RT-PCR) analysis in patients with t(8;21) acute myelogenous leukemia (AMU in long-term remission. In the present study, the AML1/ETO mRNA could be detected by RT-...
Other side effects of Jakafi Some side effects of ruxolitinib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or ...