QTc measured in rest ECG was 610 ms and maladaptation of the QT interval duration to the changing heart rate was documented. 24-hour ECG did not show significant arrhythmias. Both echocardiogram and magnetic resonance confirmed structurally normal heart. Electrophysiological study ruled out WPW ...
This hypothesis was tested by prospectively measuring the QT interval during the first week of life in more than 33,000 infants and by following them for a possible occurrence of SIDS [53]. There were 34 deaths, of which 24 were due to SIDS. The infants who died of SIDS had a longer...
The study investigated interobserver and intrasubject reproducibility of QT interval duration and dispersion measured in standard 12-lead ECGs recorded at 25 mm/sec. Twenty-eight healthy volunteers were studied. Each undenvent four ECG recordings, which were performed 1, 7, and 30 days apart. Two...
This review focuses on the molecular determinants of the duration of the QT interval as measured on by electrocardiography in normal subjects and during cardiac hypertrophy and failure. (a) In control conditions, on a single cell, the shape and duration of the action potential is the result of...
The duration of the QT interval is determined by the time of the ventricular repolarization. B: Simulated ventricular action potential in physiological situation (black trace), the rapidly activating and inactivating peak INa drives membrane depolarization; a very small sustained or late INaL is ...
When is the QT “too long”? The original descriptions of the congenital LQTS11 were based on patients with obvious prolongation of the QT interval. As commonly occurs, increased awareness on the part of the medical community led to the recognition of patients with milder forms of the disease...
Expected durationInherited long QT syndrome does not go away. If you have a long QT interval caused by a medication you are taking or by a mineral imbalance, it will most likely go away once you stop taking the medication or treat the imbalance. Note that if one type of medication causes...
16-20 We have recently shown that a history of syncope in patients with LQT3 was associated with a 12-fold increase in risk of subsequent LTE independent of other risk factors18 and can be used along with corrected QT interval duration for risk stratification prior to a decision on the ...
Lehmann MH, Timothy KW, Frankovich D et al (1997) Age-gen- der influence on the rate-corrected QT interval and the QT-heart rate relation in families with genotypically characterized long QT syndrome. J Am Coll Cardiol 29:93–99 21. Priori SG, Schwartz PJ, Napolitano C et al (2003) ...
A prolonged QT interval on ECG should raise the suspicion of a long QT syndrome (LQTS).[1] LQTS may be inherited (gene variant) or acquired (drug-induced) and generally results from a cardiac ion channel dysfunction. Human ether-a-go-go related gene (hERG) is such a typically affected ...