Long non-coding RNAs (lncRNAs) regulate cellular processes by interacting with RNAs or proteins. Transforming growth factor β (TGFβ) signaling via Smad proteins regulates gene networks that control diverse biological processes, including cancer cell mi
LncRNA NRON alleviates atrial fibrosis via promoting NFATc3 phosphorylation. Mol Cell Biochem. 2019;457:169–77. Article CAS Google Scholar Wang P, Luo ML, Song E, Zhou Z, Ma T, Wang J, et al. Long noncoding RNA lnc-TSI inhibits renal fibrogenesis by negatively regulating the TGF-β...
The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. Cell Stem Cell 2015, 16, 413–425. [CrossRef] [PubMed] 143. Wu, J.; Wang, D. Long noncoding RNA TCF7 promotes invasiveness and self-renewal of human non-small ...
LncRNA; ANRIL; 9p21 locus; cancer; gene regulation; epigenetics; competitive endogenous RNA 1. LncRNAs and Cancers The human genome is extensively transcribed into thousands of RNAs. A significant part of the resulting transcriptome corresponds to the long non-coding RNAs (lncRNAs) defined as RNAs...