LncRNADisease: a database for long-non-coding RNA-associated diseases. Nucleic Acids Res 41, D983-D986 (2013).Chen G, Wang Z, Wang D, Qiu C, Liu M, Chen X, Zhang Q, Yan G, Cui Q. LncRNADisease: a database for long-non-coding RNA-associated diseases. Nucleic Acids Res. 2013...
名词解释长非编码 RNA(long non-coding RNA,IncRNA) 答案 长非编码RNA:是一类长度为200~100000个核苷酸的RNA分子。lncRNA由RNA聚合酶Ⅱ转录生成,经剪切加工后,形成具有类似于mRNA的结构。lncRNA有poly(A)尾和启动子,但序列中不存在可读框,不编码任何蛋白质。lncRNA具有调控的多样性,可从染色质重塑、转录调控及转...
The prominent lncRNA antisense noncoding RNA in the INK4 locus (ANRIL), which has been unequivocally associated with coronary artery disease through genome-wide association studies (GWAS), serves as an example to demonstrate the features of each individual database....
然而,lncRNA在大小上存在显著差异,==长度超过10 kb的lncRNA属于超长基因间RNA (very long intergenic RNAs, vlinc)和宏观lncRNA==。这些转录本具有一些区别于其他lncRNA的特征:它们的剪接性差或不剪接,在3 '端弱聚腺苷酸化,并且由特定的基因组位点产生。大多数vlincRNA都位于同一条或相反的链上的PCG(蛋白编码...
Long Non-Coding RNA Sequencing Introduction Long non-coding RNAs (lncRNAs) are thought to encompass nearly 30,000 different transcripts in humans, hence lncRNA transcripts account for the major part of the non-coding transcriptome. lncRNA discovery is still at an early stage and only a small pr...
LncRNA (Long non-coding RNA) is a class of non-coding RNA molecules with lengths exceeding 200 nucleotides and lacking protein-coding functions.
longnon coding rna名词解释 Long noncoding RNA(LncRNA)是一类长度大于200个核苷酸的长链非编码RNA。它属于非编码基因组的重要组成部分,一些LncRNA的长度甚至超过90kb,被称为macroRNA。研究表明,LncRNA在剂量补偿效应、表观遗传调控、细胞周期调控和细胞分化调控等众多生命活动中发挥重要作用,成为遗传学研究的热点。
Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts shown to play important roles in tumourigenesis and tumour progression. Our study aimed to examine expression of the lncRNA MAGI2-AS3 in breast cancer and to explore its function in cancer cell growth. First, MAGI2-AS3 ...
NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants. Nucleic Acids Res. 49, D165–D171 (2021). Article CAS PubMed Google Scholar Uszczynska-Ratajczak, B., Lagarde, J., Frankish, A., Guigo, R. & Johnson, R. Towards a complete ...
《Long Non-Coding RNA Biology》是一本由M.R.S. Rao著的专业书籍,该书于2017年由Springer出版社出版。原著中说明了可以用于交流学习,不涉及商业用途就可以,因此不存在侵权问题。 本书是关于长非编码RNA(lncRNA)的综合性教材,涵盖了lncRNA的多个方面,包括结构、功能、调节机制、疾病相关性等等。该书共分为10章...