Long-lasting potentiation and other forms of synaptic plasticity (including long-term depression, the counterpart of long-lasting potentiation) can be impaired by certain patterns of developmental ethanol exposure, and this also could be a consequence of persistent alterations in NMDA receptor levels and...
Long-lasting potentiation is produced by a single application of 1.0 μM isoproterenol (a β-adrenergic antagonist) to the dentate gyrus. The results of the present work indicate that a much lower 75 nM concentration of isoproterenol produces long-lasting potentiation in the dentate gyrus if it ...
long-term potentiation(redirected from Long-lasting potentiation)Also found in: Dictionary, Encyclopedia. long-term potentiation n. Repeated presynaptic stimulation of a nerve, either naturally or in vitro, that results in the long-lasting increased strength of a synapse and is thought to be ...
这种现象——即高频刺激可引发突触后细胞的持久增强反应——最初被称为“持久增强作用”(long-lasting potentiation)。蒂莫西·布利斯1968年加入了安德森的实验室,与勒莫合作,二人在1973年发表了第一篇关于海马体长时程增强作用的论文。布利斯和托尼·加德纳-梅德温在同一期刊物中发表了在清醒动物身上观察到尝试成增强...
NE potentiated the population spike by 20–400%, whereas the population EPSP was rarely increased. At 39% of the potentiated sites NE application resulted in long-lasting potentiation (LLP) suggesting a role for NE in long-term hippocampal plasticity.关键词:...
(1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anesthetized rabbit following stimulation of the perforant path. Journal... T Bliss,A Gardner-Medwin - 《Journal of Physiology》 被引量: 0发表: 1973年 Acute intrahippocampal infusion of BDNF induces lasting pot...
A challenge dose of nicotine (0.4 mg kg−1 s.c.) produced a long-lasting potentiation (LLP) of field EPSPs evoked in the dentate gyrus by stimulation of the medial perforant path of urethane-anaesthetized rats primed four weeks previously with seven daily injections of nicotine (0.8 mg kg...
Wild-typea-synuclein, a protein of unknown function, has received much attention because of its involvement in a series of diseases that are known as synucleinopathies. We find that long-lasting potentiation of synaptic transmission between cultured hippocampal neurons is accompanied by an...
Sarvey, J. (1988). Protein synthesis in long-term potentiation and norepinephrine-induced long-lasting potentiation in hip- pocampus. In: Long-term Potentiation: From Biophysics to Behavior. P. Landfield and S. Deadwyler, eds. (New York: Alan R. Liss), pp. 329-353....