The article focuses on the role of opioids in medical therapy, that are used as an analgesic to get relief from chronic pain. Topics discussed include the success of aggressive opioid therapy for cancer pain treatment, accidental opiate overdose deaths from prescription opioids and the risk of ...
摘要: Opioid analgesics are commonly used for the management of chronic noncancer pain. Although they can be beneficial for select patients, opioids are also at the heart of a nationwide epidemic of misuse and diversion.关键词:Humans Opioid-Related Disorders Analgesics, Opioid Chronic Pain Risk ...
if pain was already established, females did not respond as well to the peptide compared to males. But if the peptide was administered right at the time of injury, females had a much better reduction in pain behavior than their male counterparts did. ...
"Given the high rates of chronic opioid use in women along with evidence of poor relief from pain and concerning risks, particularly in reproductive-agedwomen, we need more effective and safer options for managing pain in this population," Susan G. Kornstein, MD, Editor-in-Chief ofJournal of...
Long-term opioid vs. nonopioid therapies for the treatment of chronic musculoskeletal painLong-term opioid vs. nonopioid therapies for the treatment of chronic musculoskeletal paindoi:10.1097/EBP.0000000000000464Hess, Matthew C.Evidence-Based Practice...
Long-Lasting Regulation of Galanin, Opioid, and Other Peptides in Dorsal Root Ganglia and Spinal Cord during Experimental Polyarthritis Mechanisms involved in transition from acute to chronic pain are still not well understood and our means to therapeutically influence this transition are l... L Cal...
Intrathecal Opioid Therapy for Non-Malignant Chronic Pain: A Long-Term Perspective. Many patients with intrathecal opioid pumps do adhere to the therapy for many years but there is scarce knowledge about the long-term effects of intratheca... Barbara,Kleinmann,Tilman,... - 《Neuromodulation Jour...
PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain Acupuncture has been used for millennia to treat pain, although its efficacy and duration of action is limited. Acupuncture also has brief (1???2 h) antino... JK Hurt,MJ Zylka - 《...
1). This study for the first time provides an LA-based approach for simultaneous long-lasting postoperative analgesia and prevention of tumor recurrence. Fig. 1 A schematic illustration showing that LA-loaded hydrogels relieve post-tumor resection pain and promote the killing of residual tumor cells...
Palmitoylethanolamide (PEA) has been prescribed in neuropathic pain management for over 20 years. This study aims to summarize what has been publi