In this hypothesis generating study, the long-term effects of methylphenidate on mental fatigue, cognitive function, and safety were assessed. Materials & methodsThirty participants who suffered from long-term post-concussion symptoms after a mild TBI or moderate TBI and who had reported positive ...
Electroconvulsive therapy (ECT) is the most acutely effective treatment for depression, but is limited by cognitive side effects. However, research on thei... M Semkovska,DM Mcloughlin - 《Biological Psychiatry》 被引量: 336发表: 2010年 Long-lasting suppression of hippocampal cell proliferation ...
OBJECT: This study was designed to follow the effects of bone marrow stromal cell (BMSC) administration in rats after traumatic brain injury (TBI) for a 3-month period. METHODS: Forty adult female Wistar rats were injured by a controlled cortical impact and, 1 week later, were injected intra...
However, the effects of TBI on the expression of antioxidant enzymes in HSCs have not been studied. SOD, CAT, and GPX1 are three major cellular antioxidant enzymes. SOD converts superoxide radical into hydrogen peroxide (H2O2), whereas GPX1 along with CAT converts H2O2 into water. To ...
impaired small-world organization after TBI32,34, along with concussion studies showing connectivity changes lasting beyond RTP35,36, we hypothesized that concussed athletes would have reduced local and global network efficiency at acute injury, with effects that would not normalize until one year post...
Given the long-term effects of Covid on cognition and the negative effects of cognitive impairment on quality of life and social participation, it is important to determine whether low-dose, non-pharmacological interventions can be effective. The trial will determine which of the usual types of ...
Understanding the long-term effects of concussive events remains a challenge for the development of modern medical practices and the prevention of recurrent traumas. In this study, we utilized indices of oculomotor performance and the ability to react to
The press release states that the ability to model the mechanical forces causing the compression, stretching, twisting, and other deformations of brain tissue that lead to brain damage is critical to understanding TBI. This modeling could help researchers understand why some TBIs...
A variety of neuropsychiatric disorders have been described in 20 to 30 % of the patients suffering of acquired immunodeficiency syndrome (AIDS). Due to the fact that neurons are not directly infected with the human immunodeficiency virus (HIV), the pathophysiological manifestations of the AIDS-relat...
'This study highlights the important and as-yet unanswered question of why TBI survivors are more likely to die young, but it may be that serious brain trauma has lasting effects on people's judgement,' suggests Dr Fazel. 'People who have survived the acute effects of TBI should be more ...