LONP1(Lon protease homolog, mitochondrial) is also named as LONP, LONHS, HLON, LON, PRSS15, PIM1, MGC1498 and belongs to the peptidase S16 family. It seems to play a major role in the elimination of oxidatively modified proteins in the mitochondrial matrix(PMID:18021745). LONP1, also...
蛋白描述: lon protease homolog, mitochondrial isoform 1 precursor [Homo sapiens] 蛋白大小: 959 aa 蛋白序列: maastgyvrlwgaarcwvlrrpmlaaaggrvptaagawllrgqrtcdasppwalwgrgpa iggqwrgfweassrgggafsggedaseggaeegaggaggsagagegpvitaltpmtipdv fphlpliaitrnpvfprfikiievknkklvellrrkvrlaqpyvgvflkrddsnesdvve ...
背景资料Lon protease homolog,mitochondrial is an enzyme that in humans is encoded by the LONP1 gene.It is mapped to 19p13.3.This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases.This protein mediates the selective degradation of misfolded,unassem...
Human ATP-dependent Lon protease (LONP1) forms homohexameric, ring-shaped complexes. Depletion of LONP1 causes aggregation of a broad range of proteins in the mitochondrial matrix and decreases the levels of their soluble forms. The ATP hydrolysis activity, but not protease activity, of LONP1 is...
The mitochondrial ability to respond to organelle- specific stressors is essential for the degradation of unfolded proteins in the mitochondrial matrix [117]. The human Lon protease is highly conserved through multiple levels of evolution, and is the homolog of the bacterial La [12] and the ...
The mitochondrial Lon protease homolog (LonP1) regulates mitochondrial health by digesting proteins from the mitochondrial matrix that are damaged or must be redoi:10.1101/2021.07.28.454137Inayathulla MohammedKai A. SchmitzNiko SchenckAnnika Topitsch...
结合亚细胞定位的结果(图4),蛋白发生巴豆酰化修饰的ratio值以及蛋白的功能,我们关注到lonp1蛋白(atp-dependentmitochondrial proteases lon protease homolog(lonp1))。lonp1蛋白是atp依赖的线粒体蛋白酶lon蛋白酶同源物,是一种多功能蛋白酶,至少有三种不同的功能(蛋白水解、分子伴侣活性和mtdna结合),参与调节线粒体...
蛋白别名:h LonHS; hLON ATP-dependent protease; Lon protease homolog, mitochondrial; Lon protease-like protein; LONHs; LONP; LONP1; Mitochondrial ATP-dependent protease Lon; mitochondrial lon protease-like protein; Serine protease 15 基因别名:CODASS; hLON; LON; LonHS; LONP; LONP1; PIM1; ...
浓度:2000 ug/ml 库存:现货 Size mouse,humanCoIP Miriplatin-loaded liposome, as a novel mitophagy inducer, suppresses pancreatic cancer proliferation through blocking POLG and TFAM-mediated mtDNA replication humanWB EMBO J Stress-dependent macromolecular crowding in the mitochondrial matrix ...
Lon1 protease mutants that exhibit a post-embryonic growth retardation phenotype.• Translational fusion to yellow fluorescent protein revealed AtLon1 subcellular localization in plant mitochondria, and the AtLon1 gene could complement the respiratory-deficient phenotype of the yeast PIM1 gene homolog....