Inverse zero-order correlations for INTERMED and LOCUS total score and GAF were obtained. However, only the beta weight for LOCUS and GAF was significant. An exploratory principal components analysis further illuminated areas of convergence between the instruments.Conclusions: INTERMED and LOCUS ...
Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval. PLoS Genet. 15, e1008489 (2019). Article PubMed PubMed Central Google Scholar Manouchehrinia, A. et al. Age related multiple sclerosis severity score: disability ranked by age. Mult....
of control scores (i.e., the course of their disease is in the hands of fate) exhibit more maladaptive pain coping strategies and greater psychologic distress than patients who score high on internal locus of control (i.e., have a sense that they can control the course of their illness)...
Animals that were assessed an endpoint score of 2 for any of the above three parameters during the 14-day observation period were euthanized. Pellets collected from the mice on day 5 postinfection were tested for the presence of toxins A and B with the Wampole C. difficile TOX A/B II ...
An ISS severity score was assigned using the following criteria: 0 = normal unfused appearance; 1 ≤ one-third of the ISS width bridged by ossification; 2 = between one-third and two-thirds of the ISS bridged by ossification; 3 = the presphenoid and BS bones of the ...
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Conversely, the edu- cational level was higher in men (6.10±4.49 years versus 3.60±2.22 years; P,0.001). Men also had a higher MMSE score than women (17.57±4.41 versus 15.14±3.64; P=0.003). No differences were observed in mean values of ADL and IADL scores. Men had a higher ...
ROSMAP participants with brain DNA methylation data, which included one clinical diagnosis at time of death (AD dementia, other dementia, MCI or no cognitive impairment), and two AD-related indices (i.e., Braak stage and CERAD score). Additional information is provided in the Methods section....
The representation in the brain space is called eigenimage and show the level contribution (either positive or negative) for each voxel to the correlation mapping. Similarly, the gene loadings (positive or negative) show the contribution of each gene to the correlation mapping. The number of ...
8–11). To account for the minor inflation found in the Hispanic/Latin American samples (λ1,000 = 1.002 and linkage disequilibrium score regression (LDSC) intercept 1.051; Supplementary Table 2), we corrected test statistics for this analysis based on the LDSC intercept....