Frozen 30 μm sections were cut for characterization by immunohistochemistry and for assessment of demyelination and other pathology using previously described protocols (Dutta et al., 2006). Analysis of Hexim1 in MS patient tissue Patient demographics are listed in Table S4. Sections were washed 3...
using data from 17,996 individuals from four ancestry groups. Downstream characterization of urate-associated CpGs includes association with differential gene expression, Mendelian randomization (MR), and mediation as well as enrichment analyses. We show that significantly associated CpGs explain 11.6% of ...
46, the control region of maternally transmitted mtDNA and the cytochrome oxidase subunit I region (COI)20of maternally transmitted mtDNA47. Nuclear DNA restriction FLP in anonymous and coding regions have been developed for species identification48, targeting at least seven ...
Primary neuronal culture, immunofluorescence staining, co-immunoprecipitation, lentiviral vector production, intracranial stereotaxic injection, behavioral assessment, and drug treatment were used to examine the physiological impacts of Nischarin (encoded by NISCH). Results Deleting the Alu sequence in U251 ...
‘blend’ volume rendering, which altogether allowed a reliable discrimination of details on the cellular level. The semiquantitative assessment implied a five-grade score (0 = structure not detected; 0/ + = only one cell or extremely sparse debris in the entire scan; + ...