H. (2017). Activity-dependent formation and location of voltage-gated sodium channel clusters at a CNS nerve terminal during postnatal development. Journal of Neurophysiology, 117(2), 582-593.Xu, J., Berret, E., and Kim, J. H. (2016). Activity-dependent formation and location of voltage...
Voltage-gated Na(+) channels (VGSCs) are responsible for the rising phase of the action potential in excitable cells, including neurons and skeletal and cardiac myocytes. Small alterations in gating properties can lead to severe changes in cellular excitability, as evidenced by the plethora of her...
We examined the hypothesis that voltage-dependent properties of allow for the accurate transfer of synaptic information to the soma independent of location. This hypothesis is motivated by experimental evidence that contain a complex array of voltage-gated channels. How these channels affect synaptic int...
Elevations in the intracellular concentration of Ca can lead to the activation of transcription, and Ca entry through L-type voltage-gated channels seems to be particularly effective in this regard. So far, this effectiveness has been explained in terms of the spatial coupling of these channels ...
Voltage-gated sodium channels (VGSCs) are responsible for the initiation and propagation of action potentials in excitable cells. VGSCs in mammalian brain ... HA O'Malley,LL Isom - 《Annual Review of Physiology》 被引量: 100发表: 2015年 Sodium Channel Β Subunits: Anything but Auxiliary. Vol...
Regulation of voltage-gated ion channels by NGF and ciliary neurotrophic factor in SK-N-SH neuroblastoma cells. Neurotrophic factors have powerful effects on neuronal differentiation and the maintenance of neuronal phenotype, but understanding of their regulation of ... SS Lesser,DC Lo - 《Journal ...
Protruding from the cell body are dendrites, which are short projections of the plasma membrane that receive information from other neurons or the environment. Dendrites have receptor sites, which are ligand-gated ion channels. These receptor sites detect chemical signals from other neurons as well ...
Visual working memory (VWM) is prone to interference from stored items competing for its limited capacity. Distinctiveness or similarity of the items is ac
explained by the action potential activation of voltage-gated Ca2+ channels clustered at ‘hotspots’ on the axon plasma membrane, colocalized with synaptic release zones. In contrast, release of Ca2+ from internal stores did not contribute to the Ca2+ signal following single axonal action ...
[6]Solc C, Aldrich R (1988) Voltage-gated potassium channels in larval CNS neurons of Drosophila. J Neurosci 8: 2556–2570. pmid:3249242 [7]Tsunoda S, Salkoff L (1995) Genetic-analysis of Drosophila neurons—shal, shaw, and shab encode most embryonic potassium currents. J Neurosci 15: ...