Local Anesthetic Agents/DrugsLocal anesthetic agents are drugs that prevent the generation and transmission of action potentials by nerve cells. These drugs are sodium-channel blockers. They can be used topically by infiltration...doi:10.1007/978-3-642-28753-4_201176...
From four cases of bupivacaine-induced convulsions with concomitant hypoxia and acidosis without cardiac arrest, it is concluded that presently no data from humans or animals provide evidence that bupivacaine and etidocaine are more cardiotoxic than the shorter-acting local anesthetic drugs. Immediate ...
Toxicity caused by local anesthetic drugs 来自 ResearchGate 喜欢 0 阅读量: 24 作者:Scott,D. B.DOI: 10.1093/bja/53.6.553 被引量: 32 年份: 1981 收藏 引用 批量引用 报错 分享 全部来源 求助全文 ResearchGate onAcademic 相似文献 参考文献 引证文献...
Local anesthetic activity of beta-adrenergic blocking drugs in the Crayfish giant axon, with reference to calcium ion. Jpn J Pharmacol. 1980 Oct; 30 (5):607–619.Ishida H, Sasa M, Takaori S. Local anesthetic activity of the β-adrenergic blocking drugs in the crayfish giant axon, with ...
The Sodium Channel as a Target for Local Anesthetic Drugs A. (2011). The sodium channel as a target of local anesthetic drugs . Front. Pharmacol. 2 :68.10.3389/fphar.2011.00068 [ Cross Ref ]... HA Fozzard,MF Sheets,DA Hanck - 《Frontiers in Pharmacology》 被引量: 71发表: 2011年 ...
7 List the possible complications of epidural or intrathecal anesthetic blockade ▪ Epidural blockade involves the risk of inadvertent dural puncture. When this occurs, cerebrospinal fluid (CSF) may leak, and a postlumbar puncture (low-pressure) headache may develop. ▪ Rarely, the needle used ...
In general, anesthetic action is different from other drug effects on three points, its non-specific aspect, its very high dose compared to other drugs, an... Y Suezaki,AG Petrov - 《Journal of the Physical Society of Japan》 被引量: 0发表: 2002年 Lipid-mediated Action of Local Anesthe...
thelocalanestheticdrugs:bupivacaine,mepivacaine orropivacaine. ©2006ElsevierB.V.Allrightsreserved. Keywords:Localanaestheticdrug;Bupivacaine;Mepivacaine;Ropivacaine 1.Introduction Thelocalanestheticamidedrugs,bupivacaine,mepivacaine andropivacaine,arethemembersofthepipecoloxylididegroup (Fig.1).Thesedrugsare...
A majority of antiarrhythmic drugs have demonstrated local anesthetic effects, in that they reduce the fast inward sodium current of cardiac fibers. It is the purpose of this review to briefly discuss the contributions of local anesthetic effects to the actions of antiarrhythmic agents....
Given these limitations, it has been a long-standing goal to develop a local anesthetic sustained release system that can provide prolonged peripheral nerve blockade with minimal systemic and local side effects. Naturally occurring site 1 sodium channel blockers (S1SCBs), such as tetrodotoxin (TTX)...