Certain medications require a loading dose, or a larger one-time dose, to reach therapeutic levels within the body rapidly. Thereafter, the loading dose is followed by maintenance doses at lower levels. This medication dosing regimen is complex and strays from the usual medication administration ...
None of the included patients were taking cardioactive or antihypertensive medication in the preoperative period. Outcomes Change in blood pressure SBP, DBP and MAP increased significantly in the P+ DEX group after continuous intravenous infusion of a loading dose of DEX at T5 compared to T0 (P...
aif they had used any prescription medication within 7 days, or had imbibed a total dose of the medication equivalent to six times its elimination half-life before study drug intake, whichever was longer; 如果他们在7天之内使用了任何处方疗程或者吸取了疗程的总药量相当于六次它的排除半衰期在研究药物...
(1) The baseline data, angiography results, PCI procedure and medication among the 3 groups were not statistically different and were comparable. (2) Comparison of serum sCD40L level among the three groups: ① No significant difference was found among the 3 groups on the serum sCD40L levels ...
As a result, a variety of innovative delivery techniques were developed as a successful approach for enhancing the selectivity, solubility, curative value, release rate, and therapeutic effects of OXAP drugs and can also maintain the provided dose of the medication at the recommended quantities [11...
Twenty-four hours after the LD, all patients were started on a regimen of clopidogrel 75 mg/day and ASA ≤100 mg/day. Low molecular weight heparin was administered twice daily. All study medication was administered on an open-label basis. Patients were followed up at 30 (±7) days to ...
Clopidogrel is an established oral antiplatelet medication of thienopyridine class, which inhibits blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Many studies have revealed that high loading dose clopidogrel in patients undergoing PCI. This review article ...
55.7nmol/L (21.1);p=0.049) with lower prevalence of secondary hyperparathyroidism (10 vs. 24%;p=0.045) was observed in intervention group. No (serious) adverse events related to study medication were found. The loading dose regimen was more effective in increasing 25(OH)D in patients with ...
In summary, the present results suggest that Short Parkinson's Evaluation Scale is a useful tool in assessing the effect of medication, having the advantage of being easier and quicker. 展开 关键词: Keywords Parkinson's disease Rating scales Short Parkinson's Evaluation Scale Unified Parkinson's ...
The primary endpoint was the platelet reactivity index (PRI) measured with the vasodilator-stimulated phosphoprotein assay 2 h after intake of the study medication. Secondary endpoints were PRI after 4 h, TIMI (Thrombolysis In Myocardial Infarction) patency of the infarct-related artery before and ...