No grade 3/4 non-hematological TEAEs occurred in ≥15% of patients. SPMs were reported in 13 (5.2%) patients; 5 were reported during index LOT and 8 were reported after index LOT. Cases of SPMs included squamous cell carcinoma (n = 4), basal cell carcinoma (n = 2), ...
Risk Summary Based on its mechanism of action, LOQTORZI can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology (12.1)]. There are no available data on the use of LOQTORZI in pregnant women. Animal studies have demonstrated that inhibition of the PD-1/PD-...
Drug Summary What Is Loqtorzi? Loqtorzi (toripalimab-tpzi) is a programmed death receptor-1 (PD-1)- blocking antibody Indicated in combination with cisplatin and gemcitabine, for first-line treatment of adults with metastatic or with recurrent locally advanced nasopharyngeal carcinoma (NPC) and...
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In summary, current GNSS/IMU/LO integration solutions focus on sensor data processing or filter/graph architecture. However, robust LO error modeling is lacking, which is critical for assigning an appropriate weight to LiDAR information. Although LO error covariance matrices have been established, they...
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In summary, limonene presented an anti-inflammatory effect by decreasing ROS production, NF-κB activity and eosinophil migration. We can conclude that limonene exerted an anti-inflammatory effect on in vitro and in vivo assays mainly by modulating the action of cytokines and participating in ...
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TRF3703-33 Worst-Case Image Sideband Level With LO Filtering 8 Summary Complex I/Q modulators employing polyphase bridge circuits to generate quadrature LO signals can be susceptible to high LO harmonic levels at their input. The high harmonic content causes undesired phase shifts in the I and Q...