2. Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability. |[J]Drug DeliveryVolume 28, Issue 1. 2021. PP 252-260 3. Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Va...
基因药物递送系统:LNP与AAV背后的发展逻辑 药物递送系统(Drug Delivery System,DDS,药物传递系统)是指在空间、时间及剂量上全面调控药物在生物体内分布的技术体系。其目标是在恰当的时机将适量的药物递送到正确的位置,从而增加药物的利用效率,提高疗效,降低成本,...
2. Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability. |[J]Drug DeliveryVolume 28, Issue 1. 2021. PP 252-260 3. Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Va...
1. Aldosari et al., (2021). Lipid Nanoparticles as Delivery Systems for RNA-Based Vaccines. Pharmaceutics, 2. Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability. |[J]Drug DeliveryVolume 28, Issue 1. 2021. PP...
Learn about DIANT’s state-of-the-art equipment including the proprietary DIANT® Jet technology and our continuous closed manufacturing system. TECHNOLOGY Nanoparticle Drug Delivery Learn about nanoparticle engineering and how DIANT’s technologies can streamline the research and manufacture of LNPs...
Extend drug half-life Potential Applications Drug delivery system Modification of proteins Development of polymer materials Profacgenis a state-of-the-art protein service provider. We provide custom protein services in the biological sciences, enabling access to the latest tools, techniques, and expertis...
基于纳米药物递送系统(nano drug delivery system, NDDS)—脂质纳米粒(lipid nanoparticles, LNP)的mRNA疫苗因其较高的有效性和安全性已实现了广泛应用。尽管已有基于mRNA-LNP的新冠疫苗严重过敏反应的报道, 但目前过敏反应发生的机制和成分尚未完全明确。本文关...
深信创始人李林鲜博士在核酸药物给药系统(Nucleic Drug Delivery System, NDDS)领域有10年以上研发经验,在核酸生物、mRNA修饰、磷脂合成、制剂学等方面有系统全面的积淀。李博士展现出从科学家向科学企业家蜕变的能力,带领深信团队耐心积累、高效落地,同时整合多方资源快速推进项目。我们看好深信在mRNA及递送系统方面的...
開發藥物傳輸系統(Drug Delivery System)的目的,是能透過新的傳輸方式,將許多已被監管單位批准,或是如基因治療等新興型態(Modality)的藥物,更精確送達治療部位,以達到提升藥效、降低給藥所需劑量,同時減少副作用的成效。 從藥物型態而言,傳統化學小分子藥由於分子量小、安定性佳,容易進入細胞並被人體代謝,因此,在藥物...
最近,由于将 LNP 纳入基于信使 RNA (mRNA) 的疫苗配方,旨在防止 COVID-19 大流行的传播,因此在全球范围内受到广泛关注。LNP 纳米技术已迅速成为基因治疗和其他复杂注射药物产品的首选药物递送系统 (DDS,drug delivery system),代表了纳米医学的未来。 一、胃肠外剂型的脂质溶液...