The functional role and mechanism of lnc-LBCS are further investigated by gain and loss of function assays in vitro.#The expression of Lnc-LBCS was lower in CRPC cells lines and tissues. LBCS downregulation was correlated with higher Gleason Score, T stage and poor prognosis of PCa patients....
Castration resistance prostate Cancer (CRPC), lncRNA LBCS, Castration resistance, Androgen receptor (AR), hnRNPKBackground Progression to a castration resistance state is the main cause of deaths in prostate cancer (PCa) patients. Androgen Receptor (AR) signaling plays the central role in ...