Rituximab, a novel anti-CD20 antibody targeting B-lymphocytes, plays a central role in the current protocol in combination with tacrolimus, mycophenolate mofetil, and steroids, with or without local infusion therapy and splenectomy [34,35]. However, rituximab usually needs to be administered 2–4...
Busuttil RW,Lake JR.Role of tacrolimus in the evolution of liver transplantation.Transplantation. 2004Busuttil RW, Lake JR. Role of tacrolimus in the evolution of liver transplantation. Transplantation 2004; 77: S44-S51Busuttil RW,Lake JR.Role of tacrolimus in the evolution of liver ...
Human Trials: The Human Kidney Transplant Trials Ch01-9781455702688.indd:Anchor 229:4716 Human Trials: The Human Liver Transplant Trials of 1963 Ch01-9781455702688.indd:Anchor 230:4717 Human Trials: The Liver Transplant Moratorium Ch01-9781455702688.indd:Anchor 231:4718 Immunosuppression: Antilymphocyte...
and the target trough level of tacrolimus was 8.0–12.0 ng/ml for the first 2 weeks. Thereafter, it was tapered and adjusted to a target trough level of 5.0–8.0 ng/ml. Mycophenolate mofetil was started at 500–1000 mg/day within 5 days of the transplant in most patients and adjusted...
transplantation. Given the risks associated with percutaneous, transjugular, or operative liver biopsy in the immediate post-transplant period, liver tissue is not usually obtained unless fungal infection is a serious consideration. However, with time after transplantation, liver biopsy may be increasingly...
Modelling Tacrolimus AUC in Acute and Chronic Liver Disease Immediately after Transplant. Transplantationsmedizin 2004;16.Tolou Ghamari Z, Palizban AA, Tredger JM. Modelling tacrolimus AUC in acute and chronic liver disease immediately after transplantation. Transplant Med 2004;16:S109‑11....
The main metabolites in blood were demethyl, demethylhydroxy, didemethyl, didemethylhydroxy, and hydroxy tacrolimus. These metabolites added up to 42% (range 0-145%) of the tacrolimus concentration in liver transplant patients and to 44.8% (range 16-152%) in kidney transplant patients. ...
Conversion from Twice‐Daily to Once‐Daily Tacrolimus in Stable Liver Transplantation Patients: 2071 Lee, W.‐C.1; Chan, K.‐M.1; Chou, H.‐S.1; Lee, C.‐F.1; Wu, T.‐J.1; Wu, T.‐H.1; Soong, R.‐S.1 Login Username or Email: Password: Remember me Forgot Pass...
Tacrolimus offers total absence of chronic rejection in pediatric liver transplant recipient: followup of 7–10 years: Ashok B Jain, George Mazariegos, Randeep S Kashyap, John J Fung, Thomas Starzl, Jorge Reyes, T E Starzl Transplantation Institute, Pittsburgh, PAShow moreShow less...
Immunosuppressive effect of the gut microbiome altered by high-dose tacrolimus in mice Am J Transplant, 18 (2018), pp. 1646-1656 CrossrefView in ScopusGoogle Scholar [81] J.S. Bajaj, A. Fagan, M. Sikaroodi, M.B. White, R.K. Sterling, H. Gilles, et al. Liver transplant modulates ...