6.Cost reduction: Liver diseases, when in their early stages, are usually inexpensive to treat as compared to later stages or complications. For example, early treatment of hepatitis C might prevent cirrhosis and liver cancer, preventing the acute costs associated with managing those conditions, suc...
It is recognized as the most common cause ofcirrhosisin India. Patients with chronic alcohol intake develop pseudo-Cushingoid features like truncal obesity, moonfacies, and proximalmuscle wasting. The clinical features are nonspecific, but paper money skin and Dupuytren’s contracture are considered ...
In Japan, 40% of cases of ALF are due to hepatitis B virus (HBV) infection, whereas hepatitis E virus (HEV) causes half of cases in India and Bangladesh.1,13 Even in developed countries with extended vaccination programmes and blood product monitoring, hepatitis viruses currently account for ...
38,39], and several investigations are being conducted to enhance the availability and safety of cells [40]. Even a small amount of host hepatocytes replaced by cell therapy produces significant clinical effects in treating IEM [41]. The efficacy of cell therapy has been shown in several illnes...
Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. Dru
Journal of the Association of Physicians of India 2011.INTRODUCTION: Cirrhosis is defined as a diffuse process in the liver characterized by the development of extensive Fibrosis and replacement of the normal hepatic architecture by structurally abnormal nodules of fibrotic tissue. Because of its key ...
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In a study from India, patients with reactivation of HBV and ACLF were shown to have improved survival if they were treated with tenofovir compared with no therapy [52]. Although the ethics of this study can be questioned, it illustrates that early intervention may prevent occurrence of multi...
The complexity of the liver is such that we are unable to provide full replacement of all liver functions for any significant length of time with any of the existing systems. The critical question then becomes: What are the critical liver functions that need to be supported to improve patient...
In India, the most common cause is anti-tuberculous drugs, which are also frequently used in our population. The most frequent cause of ACLF due to DILI in Western countries is antibiotics [81,202,203]. This is why educating patients in terms of avoiding herbs use and limiting medication ...