The orange box plots on the left side in each panel show within-group changes in the aspirin group; the blue box plots on the right side in each panel show within-group changes in the placebo group; the orange and blue box plots at the far right show between-group absolute changes ...
And while we have yet to hear from Genfit on their treatment data, they didrecently announcetremendeous progress in their quest for a non-invasive diagnostic test. Using a unique 4-biomarker algorithm they have been able to accurately identify NASH and significant fibrosis. Genfit plans to file ...
Methods: CMDCK was incubated with HLMs or a panel of recombinant cytochrome P450 enzymes including CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 3A4, and 3A5. LC-ion trap mass spectrometry was used to separate and identify CMDCK metabolites. In the experiments with recombinant cytochrome P450 ...
The expression profile of a panel of 45 target genes selected among HLSC markers, β cell markers, and genes involved in glucose metabolism was tested [54]. For each selected target gene plus 3 endogenous controls, the specific TaqMan® Gene Expression Assay (Applied Biosystems) was spotted ...
In addition to a comprehensive metabolic panel measured as part of the clinical assessments in the parent trial, this ancillary study measured liver enzymes aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase; inflammation biomarker high sensitivity C-reactive protein (hs...