After excluding individuals with missing registry linkage (n = 1457), baseline liver disease (ICD-10 codes K70-K77 or C22; n = 299), chronic viral hepatitis (n = 89), or missing anthropometric measurements (n = 338), the final study cohort comprised 40,922 individuals...
The most common causes of ESLD include infection (e.g., acute or chronic hepatitis), toxic effects (e.g., alcohol, medications), disorders of metabolism (e.g., hemochromatosis, Wilson's disease), tumors (primary or metastatic), and malformations (e.g., primary biliary atresia). Liver tra...
Hepatitis B codes detected false-positive cases in patients with previous exposure (PPV 55.6%). Accuracy of codes to detect diabetes was excellent (sensitivity 95.8%; specificity 97.6%; PPV 94.9%; NPV 98.1%) with almost perfect concordance between codes and documentation in medical records (魏 ...
The specific causes of primary liver cancer in this study included hepatitis B, hepatitis C, alcohol consumption and other causes. The International Classification of Diseases (ICD-10) criteria was used to define primary liver cancer and the various specific causes of liver cancer (C22.0–C22.4,...
The recruited volunteers gave informed consent for data linkage to medical reports, which allowed the researchers to collect the available ICD codes. After excluding individuals with pathological alcohol consumption and viral hepatitis, the cohort was left with >17,000 individuals with Pi∗MZ, >800...
HCV infection, autoimmune hepatitis, primary biliary cirrhosis, acute alcoholic hepatitis, alcoholic fatty liver, unspecified alcoholic liver damage, alcoholic cirrhosis, alcohol use disorder, and chemical dependency treatment (ICD-9 and ICD-10 diagnostic codes are provided in eTable 1 in ...
The International Classification of Diseases (ICD-10) recognizes several forms of alcoholic liver disease (ALD; see ICD-10, K70), sometimes considered stages [8], that range from relatively mild and reversible alcoholic hepatic steatosis (fatty liver) (K70.0) and alcoholic hepatitis (K70.1), to...
Non-alcoholic fatty liver disease (NAFLD) is defined as excessive hepatic steatosis in the absence of specific causes (i.e., alcohol consumption, hepatitis B or C infection) [6]. Approximately 25% of adult population is affected by NAFLD currently, with worsening epidemic in recent decades coin...
1. Any of various chronic diseases of the liver characterized by the replacement of normal tissue with fibrous tissue and the loss of functional liver cells, resulting from a variety of causes that include chronic alcoholism and certain diseases and infections, especially hepatitis C. 2. Chronic ...
Drug-induced liver injury (DILI) remains an important, yet challenging diagnosis for physicians. Each year, additional drugs are implicated in DILI and this year was no different, with more than 1400 articles published on the subject. This review examines some of the most significant highlights an...