The liver morphological changes in relation to fibrosis stage in nonalcoholic fatty liver disease (NAFLD) have not yet been clearly understood. This study was to develop a liver surface nodularity (LSN) quantification program and to compare the fibrosis grades in simple steatosis (SS) and nonalco...
RESULTS: The Ishak stage scores of the livers in the control and 2, 4, 6-week groups increased when the TAA administration period was extended. L/H30 min increased with the upgrading of liver fibrosis and the differences between each pair of groups were statistically significant (p 30min in...
Liver fibrosis, as described in clinical pathology reports, was grouped into 3 severity levels: no fibrosis (stage 019), mild fibrosis (stage 119: minimal fibrosis or fibrous expansion of some portal areas, with or without short fibrous septa), or moderate to severe fibrosis (stages 2-619: ...
Stage 4 fibrosis, or cirrhosis, represents the end stage of this process and as described previously, Hepatitis B, C and alcohol-related liver disease are likely to be soon overtaken by NAFLD as its leading cause. Early detection and monitoring of fibrosis is therefore of critical importance. ...
Galectin-3, a -galactoside-binding animal lectin, is a multifunctional protein. Previous studies have suggested that galectin-3 may play an important role ... K Nomoto,K Tsuneyama,HOA Aziz,... - 《Journal of Pathology》 被引量: 74发表: 2010年 End-stage nonalcoholic fatty liver disease: ev...
diamidino-2-phenylindole (DAPI). For double staining, after completing the first protein staining, the sections were then re-incubated, and the secondary protein was detected. The liver fibrosis stage was assessed by the Ishak scale [60].
2–5 Liver biopsy may yield false-negative results in up to 30% of cases.2,4,6 Moreover, biopsy is invasive and cannot be used repeatedly in follow-up. Therefore, there is a need for a simple, reliable, non-invasive technique to assess the liver fibrosis stage and cirrhosis.7 Non-...
353 USEFULNESS OF VTTQ. (VIRTUAL TOUCH TISSUE QUANTIFICATION) TO DIAGNOSE FIBROSIS STAGE AND LIVER TUMORS 来自 Semantic Scholar 喜欢 0 阅读量: 34 作者: H.,Tanaka,and,H.,Iijima,and,M.,Yoshida,and,T. 摘要: This paper investigates the finite-sample properties of a pre-test estimator for ...
Long noncoding RNAs (lncRNAs) play important roles in various biological processes such as proliferation, cell death and differentiation. Here, we show that a liver-enriched lncRNA, named liver fibrosis-associated lncRNA1 (lnc-LFAR1), promotes liver fibr
To investigate the potential role of miR-378a-3p in its clinical implications, we analysed the expression of miR-378a-3p and its target,gli3, in non-tumour and tumour regions of liver tissues obtained from 18 patients with hepatocellular carcinoma (HCC) and advanced fibrosis (stage F3 or F4...