The Fibrosis-4 (FIB-4) Index for Liver Fibrosis is a non-invasive scoring system based on several laboratory tests that help to estimate the amount of scarring in the liver.
FIB-4 score values were also related to symptomatic intracranial hemorrhage (p = 0.004), specifically among patients with high probability of advanced hepatic fibrosis (p = 0.037). FIB-4 score can be considered as a promising independent predictor of poor prognosis in patients with acute ischemic...
FIB-4 Index Panel with Reflex to Enhanced Liver Fibrosis (ELF) Score - This reflex provides a cost-effective, medically justified, and guideline supported approach to evaluating a patient at risk of NAFLD with liver fibrosis. If the FIB-4 index is ...
Liver fibrosis is associated with lifestyle-related diseases, including diabetes. The identification of diabetic patients with severe liver fibrosis is imp
We defined liver fibrosis as: likely advanced fibrosis (FIB-4 > 3.25), indeterminate (FIB-4 range 1.45–3.25), unlikely advanced fibrosis (FIB-4 < 1.45). Primary outcomes were HFrEF and HFpEF (defined using ICD-9 diagnoses for HF, and EF extracted from electronic medical records using ...
FIB-4 as a continuous variable showed a significant association with both advanced fibrosis (P < 0.001) and cirrhosis (P < 0.001) in univariate analysis. FIB-4 > 3.25 was significantly associated with both advanced fibrosis (P = 0.001) and cirrhosis (P < 0.001). The...
Internal and Emergency Medicine (2024) 19:745–756 https://doi.org/10.1007/s11739-023-03441-2 IM - ORIGINAL Accuracy of a sequential algorithm based on FIB‑4 and ELF to identify high‑risk advanced liver fibrosis at the primary care level Pablo Gabriel‑Medina1,2,3...
However, the performance of APRI for assessing liver fibrosis was not so satisfactory in HBV patients, with an AUROC of 0.74 for significant fibrosis, 0.73 for advanced fibrosis, and 0.73 for cirrhosis [17]. FIB-4 = [age (years) × AST (U/L)] / [platelet (109/L) × ALT (U/L) ...
Advanced fibrosis (grade F3-F4) "is a major risk factor for severe outcomes," said Gastaldelli. A Fib-4 test result below 1.3 indicates low risk for advanced liver fibrosis, 1.30-2.67 indicates intermediate risk, and above 2.67 indicates high risk. ...
FIB-4, fibrosis-4; MAFLD, metabolic associated fatty liver disease; NLR, negative likelihood ratio; NPV, negative predictive value; PLR, positive likelihood ratio; PPV, positive predictive value. The diagnostic accuracy of conventional non-invasive scoring systems was evaluated by the receiver operatin...