Fibroblast cell lines from Abcc1 knockout mice show a similar resistance pattern (Lin et al., 2002), along with sensitization to taxanes and mitoxantrone. ABCC1 also mediates resistance to TKIs, such as imatinib (Czyzewski and Styczynski, 2009). 1.3 ABCC10/MRP7 transporter The human ABCC10...
Development of a transformed swine fibroblast cell line was successful, resulting in an in vivo malignant tumor. Cell line inoculums had tumorigenic properties in nude mice, wild-type mice, and immunosuppressed swine, as judged by uncontrolled cell growth, invasion of surrounding tissue, neo...
Here we describe the application of the technique to an investigation of the effects of rat liver cytoplasm on gene expression by mouse fibroblast nuclei. We show that the synthesis of mouse tryosine amino transferase (TAT)鈥攁 liver-specific enzyme never detected in the fibroblast cell line ...
Blotchy fibroblast-11细胞;细胞背景资料:详见相关文献介绍;细胞传代方法:1:2-1:3传代;每周换液2-3次。;细胞生长特性:贴壁或悬浮,详见细胞说明书部分;细胞形态特性:详见细胞说明书;相关细胞有:Mevo细胞、OCI-AML-3细胞、UMC11细胞 NCI-H510细胞;细胞背景资料:详见相关文献介绍;细胞传代方法:1:3-1:8传代;每周换...
When liver parenchymal cells were cocultured with a rat liver fibroblast cell line the gap junctional communication between the parenchymal cells was not stabilized (43% after 3 d), and isolated plasma membrane vesicles of the fibroblast were also unable to support the GJIC in parenchymal cells (...
LIGHT exerts biological effects by binding to two receptors in the TNF receptor superfamily, herpesvirus entry mediator (HVEM, or TNFRSF14) and lymphotoxin β receptor (LTβR, or TNFRSF3), which are broadly expressed in macrophages, fibroblastic reticular cells, dendritic cells, neutrophils, and...
Murine fibroblast cell line NIH-3T3, hepatoma cell line Hepa1-6, and primary murine liver cancer cells were grown in Dulbecco’s Modified Eagle’s Medium supplemented with 10% fetal bovine serum (FBS) (Gibco), 100 IU/ml penicillin (Gibco), and 100 μg/ml streptomycin (Gibco) at 37 °...
Natural killer T cell/IL-4 signaling promotes bone marrow-derived fibroblast activation and M2 macrophage-to-myofibroblast transition in renal fibrosis. Int J Immunop- harmaco. 2021;98:107907. 24. Fu C, Jiang L, Hao S, Liu Z, Ding S, Zhang W, et al. Activation of the IL-4/ STAT...
Briefly, MPCCs were first treated with B/B Homodimerizer (0.5 μM) for 30 minutes at 37°C to partially deplete the fibroblast cells via apoptosis (Chen et al., 2020). After washing, the cultures were dissociated by Trypsin (0.25%) 5-minute treatment at 37°C. A suspension with 10,...
Fibroblast membrane sterol kinetic domains: modulation by sterol carrier protein 2 and liver fatty acid binding protein. J Lipid Res 37: 1862-1874, 1996.Frolov AA, Woodford JK, Murphy EJ, Billheimer JT, Schroeder F (1996) Fibroblast membrane sterol kinetic domains: modulation by sterol carrier ...