急性肝衰竭(acute liver failure, ALF) 急性肝衰竭的特征是起病急,发病2周内出现以Ⅱ度以上肝性脑病为特征的肝衰竭症候群 亚急性肝衰竭(subacute liver failure, SALF) 亚急性肝衰竭起病较急,发病15d～26周内出现肝衰竭症候群 慢加急性/亚急性肝衰竭(acute/subacute-on-chronic liver failure, ACLF) 慢加急...
It’s the final stage of many liver diseases. But a rarer condition, known as acute liver failure, happens rapidly -- in as little as 48 hours. When working properly, the liver's main job is to filter the blood coming from the digestive tract, before passing it to the rest of the ...
It is an end-stage chronic liver disease associated with several serious systemic complications, which result from portal hypertension leading to liver failure. The major cause of liver cirrhosis include hepatitis B virus (HBV), hepatitis C virus (HCV), and alcohol consumption. Several other ...
Orthotopic liver transplantation is the only therapeutic choice in end-stage liver disorders such as cirrhosis, chronic hepatitis, ALF, chronic hepatic failure or metabolic diseases [35]. Contraindications for liver transplantation are malignancy, irreversible brain damage, uncontrolled infection, and severe...
Children with liver failure may have an acute respiratory failure following one or several simultaneous insults including hepatic encephalopathy, volume overload, pulmonary hemorrhage, pulmonary edema, acute lung injury, and other comorbidities such as ascites with intra-abdominal hypertension, hydrothorax, ...
目前供肝资源通常依据终末期肝病模型(model for end-stage liver disease,MELD)或MELD-Na评分分配,但该模型评分可能会低估ACLF的严重程度。在预测ACLF的病死率方面,慢性肝衰竭联盟ACLF(Chronic Liver Failure Consortium ACLF,CLIF-C,ACLF)优于MELD评分。
for the Study of the Liver – Chronic Liver Failure Consortium; IL-, interleukin; INR, international normalised ratio; MAP, mean arterial pressure; MELD, model for end-stage liver disease; NACSELD, North American Consortium for the Study of End-stage Liver Disease; OF, organ failure. ...
The pathogenesis of Acute-on-chronic liver failure (ACLF) involves several forms of cell death, such as pyroptosis, apoptosis, and necroptosis, which consist of PANoptosis. To explore PANoptosis as a regulated cell death pathway in ACLF. Firstly, a bioin
: Metastatic liver disease and fulminant hepatic failure: Presentation of a case and review of the literature. Eur. J. Gastroenterol. Hepatol 2003; 15: 1235–1240 PubMed Google Scholar Bartlett, D.L., Libutti, S.K., Figg, W.D., Fraker, D.L., Alexander, H.R.: Isolated hepatic ...
The North American Consortium for the Study of End-Stage Liver Disease's definition of acute-on-chronic liver failure (NACSELD-ACLF) as two or more extrahepatic organ failures has been proposed as a simple bedside tool to assess the risk of mortality in hospitalized patients with cirrhosis. We...