DOGSHEPATOTOXICITYMANAGEMENTDISEASEAcute liver failure is a syndrome with poor prognosis, with idiosyncratic drug injury being associated with a particularly poor outcome in both veterinary and human medicine. This case report presents a 4-year 9-month-old, male, entire Eurasier with history of ...
Prognosis The prognosis for ALF depends upon the etiology, the degree of liver damage, and the response to therapy. In veterinary medicine, the prognosis is generally poor. 展开 关键词: hepatic failure hepatic encephalopathy hepatic function metabolic brain disease ...
The hallmarks of chronic liver failure in dogs are fibrosis and nodular regeneration, but other species are more prone to a fibrotic response alone. The progressive loss of critical functional hepatic mass caused by ongoing hepatocyte injury, shunting of portal blood within fibrous septa bypassing ...
Changes in the metabolic profile are highly sensitive to internal and external challenges in biological systems. Thus, comprehensive metabolome information has great value in the diagnosis and prognosis of various diseases. In this study, we used liver failure animal models to determine changes in the...
Hepatorenal syndrome, which is characterized by renal failure, hemodynamic changes in arterial circulation and abnormalities in the endogenous vascular system, is a common clinical complication of end-stage liver disease, and one of the important indicators for the prognosis of patients with severe hepat...
Acute liver failure (ALF) is a widespread problem with typically unfavorable prognosis. With the implementation of a liver support device in the clinical setting for treatment of patients with ALF, anticipated improvements include prolonging time available for spontaneous recovery and bridging to liver ...
Dogs with extensive fibrosis and remodeling develop portal hypertension and ascites. Rare cases with fulminant hepatic failure display centrilobular hemorrhagic necrosis due to vascular inflammation and loss of sinusoidal endothelium. Widespread distribution of petechia ...
in practice.43Incatshyperammonemia is even less common than in dogs likely because of their high-functioning urea cycle pathways14; the assays have not been validated for feline blood in most laboratories, and as such, the test is not recommended as the sole indicator of hepatic failure. In ...
(especially viral infection), exposure to toxins (including alcohol and drugs), autoimmune reactions, and heart failure.Portal hypertensionandmetabolic diseases, such asWilson's diseaseandhemochromatosis(an excessive buildup of iron), also can cause significant liver problems. In addition, the liver ...
failure showed that the impaired synthesis capacity of the liver is reflected in the patterns of both groups of enzymes in serum. In acute viral hepatitis, the prognostic value of plasma-specific enzymes is better than that of cellular enzymes in serum, while in coma, success of hemo-perfusion...