Liver fibrosis is a growing global health problem characterized by activated hepatic stellate cells (HSCs) and excess deposition of fibrillary collagen [1]. Without effective intervention, it would likely progress to cirrhosis, liver failure, and even hepatocellular carcinoma [2]. Regulation of the ac...
BMI gain and dietary characteristics are risk factors of MASLD in non-obese individuals Hirokazu Taniguchi Miho Ueda Takatomo Shima ResearchOpen Access21 Jan 2025 Scientific Reports Volume: 15, P: 2606 The association of frailty and bedside body composition tools with total body potassium and ...
This review provides a multiorgan system–based description of critical care management of acute liver failure and acute on chronic liver failure before liver transplantation. Introduction Hepatic decompensation in the pretransplant critical care setting can present in 2 distinct contexts, which include ...
AST: High levels may indicate liver cell damage, hepatitis, heart attack,heart failure, or gall stones. ALP: Elevated levels occur in diseases that impair bile formation (cholestasis). ALP may also be elevated in many other liver disorders, as well as some lung cancers (bronchogenic carcinoma)...
Ammonia levels are orchestrated by a series of complex interrelated pathways in which the urea cycle has a central role. Liver dysfunction leads to an accumulation of ammonia, which is toxic and is strongly associated with disruption of potassium homeost
BACKGROUND: Superimposed non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) may affect HCV-related fibrosis. We performed a... R Ferguson - 《Journal of Clinical Gastroenterology》 被引量: 0发表: 2004年 Low Serum Potassium Levels Associated with Disease Severity in...
Acute liver failure (ALF) is a life-threatening disorder that progresses from self-limiting acute liver injury (ALI). Microcirculatory disturbance characterized by sinusoidal hypercoagulation and subsequent massive hypoxic hepatocyte damage have been proposed to be the mechanism by which ALI deteriorates ...
4. Clinical nutrition in acute liver failure part 1 (ALF, acute liver failure; EN, enteral nutrition; ONS, oral nutritional supplements; PN, parenteral nutrition). Fig. 5. Clinical nutrition in acute liver failure part 2 (ALF, acute liver failure; EN, enteral nutrition; ONS, oral ...
Thus, comprehensive metabolome information has great value in the diagnosis and prognosis of various diseases. In this study, we used liver failure animal models to determine changes in the levels of serum metabolites that can be identified before conventional biochemical markers. Two pig models were...
failure [14]. Laboratory findings are elevated serum aspartate aminotransferase/alanine aminotransferase (AST/ALT), hypoglycemia, elevated levels of bilirubin and blood ammonia, low platelet count, and low fibrinogen. If it is not diagnosed and treated promptly, AFLP can result in high maternal and ...