measurable metastatic disease based on RECIST v1.1; peripheral blood levels of IgG anti-β-glucan antibody (ABA) of > 20 mcg/mL; willing to consider providing fresh tissue for biomarker analysis; ECOG performance status 0 or 1; life expectancy ≥ 3 months; and adequate end organ function....
Current results have shown that there were limited treatment efficacy once patients were progressed to liver metastases, since their disease is incurable and their life expectancy is dreadfully short. In order to improve the survival of these patients, however, there are more liver-directed treatment...
cirrhosis - High Protein Diet For Good Health I have low protein levels due to stage 4 liver disease and bridge fibrosis. Is there anything that can be done to improve the protein levels to decrease the retention of fluid in my body? Stage 4 liver disea
Key Words: Alcoholic liver disease; Alcoholic hepatitis; Maddrey discriminant function score; Model for end-stage liver disease score Citation: Soultati AS, Dourakis SP, Alexopoulou A, Deutsch M, Vasilieva L, Archimandritis AJ. Predicting utility of a model for end stage liver disease in alc...
Additionally, a visual graphical representation of the agreement was created, based on the agreement chart proposed by Bangdiwala[29]. All statistical tests were considered significant for a P value < 0.05. Data were analysed using Stata/MP version 17.0 (Statacorp LP, TX, United States) and ...
Liver is the most common organ for distant metastases of PDAC, and even after curative surgery for resectable disease, more than 62% of patients will develop multiple liver metastases [3], [4]. Patients with pancreatic ductal adenocarcinoma and synchronous liver metastases, PACLM, face an even ...
a neurodegenerative disease associated with diabetes mellitus, optic atrophy and a decreased lifespan (OMIM 222300).CISD2-null mice showed early senescence and shortened life span compared to wildtype mice42. Interestingly, transgenic overexpression ofCISD2in mice increased lifespan, possibly by an int...
Median size of the largest tumor was 13 cm (range, 3–24 cm); 33 patients (63.5%) had tumor involvement > 50% of total liver volume; majority (98.1%) had BCLC stage C disease. 34 patients (65.4%) received no prior treatment. 23 patients (45.1%) were treated with Sorafenib...
Hepatic encephalopathy (HE) is a clinically significant complication of liver cirrhosis impacting on the patients’ quality of life. Minimal hepatic encephalopathy (MHE) is diagnosed by psychometric tests, found in up to 80 % of patients with liver cirrhosis and carries a high risk of progression ...
2.4. Non-Alcoholic Fatty Liver Disease Evaluation NAFLD was assessed according to the fatty liver index (FLI), which is a useful non-invasive surrogate predictor of NAFLD, by using an algorithm based on BMI, WC, triglyceride (TG), and gamma glutamyl transferase (GGT), where FLI = (e0.953...