Metallothionein immunohistochemistry has high sensitivity and specificity for detection of Wilson disease Article 21 December 2021 Response to iron overload in cultured hepatocytes Article Open access 03 December 2020 Abbreviations BA: biliary atresia; HBV: hepatitis B virus; KP: Kasai's procedur...
Abnormal Iron Levels Can Trigger Liver DiseaseSandy Rovner
The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease, iron regulation may be disturbed. Higher iron levels are present not only in patients with hereditary hemochromatosis, but also in those with alcoholic liver disease, nonalcoholic fatty liver disease, ...
As the main organ of storing excess iron,liver is the first target organ damage when iron overload.However,the relation between nonalcoholic fatty liver disease and iron overload is still controversial.More and more studies have shown that iron overload in the development of nonalcoholic fatty ...
ABSTRACT:The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease, iron regulation may be disturbed. Higher iron levels are present not only in patients with hereditary hemochromatosis, but also in those with alcohol
Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice Abnormal iron accumulations are frequently observed in the brains of patients with Parkinson's disease and in normal aging. Iron metabolism is regulated in... MF Salvatore,B Fisher,SP Surge...
alcoholic liver disease; alcoholic cirrhosis; protein–energy malnutrition1. Introduction Alcohol use disorders (AUDs) are among the leading causes of preventable diseases and liver disease-related deaths in the United States and the world. However, the prevalence of AUD and alcohol-related liver ...
iron overload) is a metabolic disorder that leads to abnormally elevated iron stores in the body. The excess iron may accumulate in the tissues of the liver, pancreas, and heart, which can lead to inflammation, cirrhosis, liver cancer, and liver failure. Hemochromatosis is aninherited disease....
Elevated levels of AST and ALT may signify the level of liver damage in a person. The interpretation of elevated AST and ALT results depends upon the entire clinical evaluation of an individual, and so it is best done by physicians experienced in evaluating liver diseaseand muscle disease. ...
Diffuse liver disease is multifactorial and may arise from metabolic, storage, vascular or neoplastic disease or from drug-related toxicities. Metabolic disease, in particular non-alcoholic fatty liver disease and its sequela of cirrhosis, is an increasi