Background/purpose The aim of this study is to evaluate a new scoring system, called the chronic liver dysfunction (CLD) score, for prediction of the surgical risk of partial hepatectomy in patients with chronic liver damage. Morbidity and mortality rates after gastroenterological surgery are high ...
Intestinal mucosal oxidative damage and bacterial translocation in cirrhotic rats. Eur J Gastroenterol Hepatol. 2003;15:145–50. Article PubMed Google Scholar Ramachandran A, Prabhu R, Thomas S, Reddy JB, Pulimood A, Balasubramanian KA. Intestinal mucosal alterations in experimental cirrhosis in ...
The diagnosis of DILI remained a challenge in 2020. As there is still no single definitive biochemical test, DILI remains a diagnosis of exclusion. Causality assessment tools, such as RUCAM, have gained increasing acceptance as demonstrated by Teschke and Danan who found that RUCAM was used to a...
Waitlisted patients with nonresolving severe acute kidney injury for 6-8 weeks or substantial irreversible renal parenchymal damage are also deemed appropriate candidates. Many combined liver-kidney recipients have lesser degrees of renal dysfunction, however. Accurate determination of renal function in ...
Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage. Hepatology 47(2), 592–595. https://doi.org/10.1002/hep.22056 (2008). Article CAS PubMed Google Scholar Dechêne, A. et al. Acute liver failure is associated with elevated liver stiffness ...
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess liver triacylglycerol (TAG), inflammation, and liver damage. The go... KL Donnelly,CI Smith,SJ Schwarzenberg,... - 《Journal of Clinical Investigation》 被引量: 3046发表: 2005年 Overproduction of cholesterol ...
In this study we investigated the effects of the novel myeloperoxidase (MPO) inhibitor AZM198 on obesity, liver damage and cardiac function in an obese and hypertensive mouse model, provoked by a high fat diet (HFD) combined with angiotensin II (AngII) infusion (HFD/AngII model). Our data ...
Acute liver failure (ALF) is a severe condition characterized by rapidly progressive liver injury, hepatic encephalopathy, and impaired synthetic function, which results in coagulopathy. The most c...
NAFLD comprises a wide spectrum of liver damage, ranging from simple macrovesicular steatosis, liver inflammation, fibrosis, and cirrhosis1,2,3. Liver biopsy has been regarded as the reference standard for diagnosing hepatic inflammation, fibrosis and cirrhosis in NAFLD. However, this method has ...
391 In addition, activated B cells produce pro- or anti-inflammatory cytokines, immunoglobulins, activate T cells, and may also exacerbate tissue damage and liver fibrosis.392,393,394 In short, there are complex immune mechanisms during NAFL/NASH; however, the current understanding of the ...