Dogs with chronic Leptospira-associated hepatitis may present for clinical and clinicopathologic features charactering chronic liver injury with portal hypertension, APSSs, and ascites. Microscopic Hepatic Findings Leptospirosis infection causes vasculitis and endothelial da...
However, in dogs with FS, the damage in the proximal tubules that is responsible for the clinical symptoms has not been evaluated. Among FS cases, tubular damage in acquired FS is reversible following the elimination of a causative factor. Liver-type fatty acid-binding ...
Immune regulation of neuronal function. The pathways in which immune influences on the nervous system consist of cytokines, afferent neural inputs, and chemoreceptors (including osmoreceptors, ion receptors, and metabolic substance receptors).DAPMsdamage-associated molecule patterns, GLUT2 glucose transpor...
Gazzard BG, Portmann B, Murray-Lyon IM, Williams R (1975) Cause of death in fulminant hepatic failure and 59. relationship to quantitative histological assessment of parenchymal damage. Q J Med 44: 615–626 PubMedCASGoogle Scholar Geiger A, Magnes J, Tailor AM, Veralli M (1954) Effect o...
Brief elevation of hepatic enzymes due to liver ischemia in anorexia nervosa Abnormal liverunction isccasionallybserved in patientsffectedynorexia nervosa.lthough numeroustudieseporttrongelationetweenalnutritionnd liver damage,he pa... Giordano,Arnone,Santeusanio,... - 《Eating & Weight Disorders Ew...
10 However, despite lacking integrase capabilities, vector sequences (usually truncated or rearranged) may integrate into the host cell genome at sites of DNA damage and fragility. Although not fully resolved, there is evidence suggesting the majority of long-term transgene expression derives from ...
Rats exposed to NMP for 10 weeks at 1000 mg kg−1 per os led to gonadotoxicity, producing male infertility and extensive damage to the seminiferous epithelium in the seminal tubules of the testis. However, subchronic exposure to NMP did not significantly affect fertility or spermatogenesis ...
There has been limited success in the development of suitable large animal models of acetaminophen induced liver injury. In the study described here we used bed-side biochemical and invasive haemodynamic monitoring during acetaminophen-induced liver damage in a reproducible and controlled manner. Using ...
Although our diagnostic techniques continue to improve, in most instances imaging and biochemical testing cannot replace a liver biopsy. This is by far the best examination for a definitive determination of the nature and extent of hepatic damage and to appropriately direct the course of treatment. ...
the course of steroid-induced hepatopathy are initially subclinical, but the changes in the structure and function of hepatic stellate cells may become a cause of lesions in the wall of hepatic sinusoidal vessels, which may induce additional functional pathologies unrelated to the damage to ...