The reaction by which thyroxine (T4) undergoes monodeiodination in the nonphenolic ring to form 3,3′,5′-triiodothyronine (reverse-T3) has been studied in rat liver. In whole homogenate the conversion of T4 to rT3 is obscured by rapid degradation of the product, whereas in cytosol accumulati...
(1977) Induction of the thyroxine (T4) to triiodothyronine (T3) converting enzyme in rat liver by thyroid hormones and analogs. Clinica Chimica Acta 80 , 61-66 Online publication date: 1-Oct-1977. /Grussendorf M. and Hefner M., Clin Chimica Acta 80: 61, 1977....
Conversion of T4 to T3 is the first step in TH action and deiodinases are the major determinants of TH tissue availability and disposal. We here report the kinetic characterization of the outer-ring deiodinating (ORD) enzymes in the liver, gill and retina of sea water-adapted killifish, by...
The local conversion of T4 as a source of intracellular T3 in several organs of both hypothyroid and euthyroid rats has recently been recognized to be an i... VAN DOORN J.,VAN DER HEIDE D.,ROELFSEMA F. - 《Endocrinology》 被引量: 98发表: 1984年 Effects of estradiol benzoate on 5'-io...
of the conversion of [...] sdvma.com sdvma.com 並且,因為肝臟是損傷從被氧化的和馊油發生造成细胞膜損傷的主要地方,並且,因為肝臟是許多T4轉換嚮T3發生的地方,消滅長鏈脂肪酸從飲食和替换他們用在椰子油找到的中等鏈脂肪酸及时在重建细胞膜和增 加將協助促進T4轉換對T3激素的酵素生產的,幫助能。
conversion of T4 to T3 hormones. sdvma.com sdvma.com 並且,因為肝臟是損傷從被氧化的和馊油發生造成细胞膜損傷的主要地方,並且,因為肝臟是許多T4轉換嚮T3發生的地方,消滅長鏈脂肪酸從飲食和替换他們用在椰子油找到的中等鏈脂肪酸及时在重建细胞膜和增加將協助促進T4轉換對T3激素的酵素生產的,幫助能。
This study examines (a) the effects of aging on plasma thyroid hormone concentration and (b) in vivo binding and cytoplasmic distribution of thyroid hormones as well as the conversion of thyroxine (T4) to triidothyronine (T3) in liver and cerebral hemispheric tissue. The results show that (a...
To investigate mechanisms of extrathyroidal thyroid hormone metabolism, conversion of thyroxine (T(4)) to 3,5,3'-triiodothyronine (T(3)) and degradation of 3,3',5'-triiodothyronine (rT(3)) were studied in rat liver homogenates. Both reactions were enzymatic. For conversion of T(4) to T...
Rat kidney homogenates, in phosphate-EDTA buffer, consistently catalyzed the formation of T3 from added L-thyroxine (T4). The formation of T3 was assessed by both paper chromatography and RIA of T3. Conversion of T4 to T3 appeared to be ... CHIRASEVEENUPRAPUND P.,BUERGI U.,GOSWAMI A....
Values for the percentage conversion of T 4to T3 in mixtures of +maternal microsomes and fetal cytosol (1.39 0.57) were signifi- For the three sets of maternal and fetal enzyme examined + +concomitantly, values for the K, of the maternal enzyme averaged 7.1 1.3 x 10-% and for the fetal...