The systemic and hepatic alternative renin–angiotensin system is activated in liver cirrhosis, linked to endothelial dysfunction and inflammation Lukas Hartl , Benedikt Rumpf & Thomas Reiberger Article 21 December 2022 | Open Access Convolutional neural network for automated segmentation of the live...
Liver cirrhosis results from chronic hepatic damage and is characterized by derangement of the organ architecture with increased liver fibrogenesis and defective hepatocellular function. It frequently evolves into progressive hepatic insufficiency associ
It can progress and lead to liver fibrosis, cirrhosis, and even liver cancer, which seriously endangers people's health [2,3,4]. The pathogenesis of ALD is complex and diverse, and many factors interact with each other. The main influencing factors are oxidative stress related to alcohol ...
specificity for cirrhosis reached 0.98 using RTCI; however sensitivity reduced to 0.65. In this pilot study, the assessment of the hepatic vein morphology has been shown to be a good indicator of cirrhosis with favourable inter- and intraobserver error. While validation with more rigorous clinicopath...
The patients with Miz1 low expression were associated with advanced cirrhosis state, pathological tumor-node-metastasis (pTNM) stage, and larger tumor size (Table S2) and had a higher probability of a worse overall prognosis and early tumor recurrence (Figures 7H and 7I). In Cox proportional ...
MR elastography, a new technique to detect liver stiffness, has not been demonstrated to detect NAFLD, and is still undergoing research in patients with hepatitis and cirrhosis. In conclusion, all these imaging tools are limited in their ability to detect coexisting inflammation and fibrosis. In ...
857 \\{TRIPLE\\} \\{THERAPY\\} \\{FOR\\} \\{HEPATITIS\\} C \\{VIRUS\\} (HCV) \\{INFECTION\\} \\{IN\\} \\{PATIENTS\\} \\{WITH\\} \\{COMPENSATED\\} \\{LIVER\\} CIRRHOSIS: \\{LESSONS\\} \\{LEARNED\\} \\{FROM\\} \\{THE\\} \\{FIRST\\} REAL-WORLD \\{...
(MAFLD) has become the most prevalent non-communicable liver pathology9. MAFLD ranges from presymptomatic hepatic steatosis (fatty liver) to non-alcoholic steatohepatitis, which is characterized by inflammation, hepatocellular injury and fibrosis, and may progress to liver failure, cirrhosis and ...
Patient 4, a non-Hispanic Caucasian female that had an increased BMI, was the only patient who had well-developed cirrhosis at the time of her first biopsy. This patient started alpha-interferon/Ribavirin approximately three years after her first biopsy was obtained and failed treatment. Two year...
Liver stiffness measurement by acoustic radiation force impulse is useful in predicting the presence of esophageal varices or high-risk esophageal varices among patients with HCV-related cirrhosis J Gastroenterol (2013 Sep 5) Mueller et al., 2010 S. Mueller, G. Millonig, L. Sarovska, S. Fried...