Sometimes, cancer may arise in the cells of the liver itself. Cancer of the hepatocytes (the main functioning liver cell) is a primary liver cancer called hepatocellular carcinomaor hepatoma. Hepatoma usually grows in the liver as one or more round tumors, invading and destroying the normal tiss...
In select areas of Asia and Africa, HCC is the most common cause of death due to cancer. The incidence in Europe and the United States is relatively low but is increasing. In Europe, HCC is now the leading cause of death among patients with cirrhosis. In the United States, epidemiologic...
CANCER OF THE BILIARY TRACT AND PANCREAS Primary cancers of the liver, extrahepatic bile ducts and pancreas comprise an important group of human neoplasms totalling between 5 and 10 per cent of all carcinomas. The hopeless prognosis of malignant growths in these areas may in pa... HM Lemon,...
AJCC cancer staging manual. 7th ed. New York: Springer; 2010. The prognosis of HCC depends not only on an anatomic assessment of the tumor, but also on the extent of underlying liver cirrhosis. The Child-Pugh scoring system remains the most commonly used tool for assessing cirrhosis.45–45...
Primary liver cancer comprises HCC, ICC, cHCC-ICC, which are markedly distinct in their epidemiology, clinical features and response to therapy • HCC is viral infection-related malignancy with specific histological features, whereas ICC is associated with chronic liver inflammation • HCC is prone...
Liver cancer is one of the most malignant cancers worldwide with poor prognosis. Intracellular mediators like microvesicles (MVs) and cancer stem cells (CSCs) are considered as potential candidates in liver cancer progression. CSCs receive stimuli from the tumor microenvironment to initiate tumor format...
Exposure to toxic chemicals, physical injury, and blockage of the bile ducts call also cause liver damage. Liver cancer can either develop first in the liver (primary liver cancer) or spread there from another site (metastasized cancer). About 16,000 new cases of primary liver cancer are ...
that are found in the liver can form different types of tumors. These tumors can either be cancerous (malignant) or non-cancerous (benign). The treatment of liver cancer depends on the kind of tumor, the cause, number and size of the tumor. Each of these tumors have different prognosis...
In this review, we address the current knowledge regarding hepatic innate lymphocytes with unique characteristics, including NK cells, ILC1/2/3s, NKT cells, γδ T cells, and MAIT cells, and their potential roles in liver homeostasis maintenance and the progression of liver diseases and cancer....