Liver cancer cell lines have been widely used for research and have proved to be a useful tool to understand the regulation of cellular events, such as uncontrolled cell proliferation, evasion of cell death, cell migration, invasion, and metastasis. There are several liver cancer and normal cell...
Althoughtumorigenicity assays in mouse are present, no established liver cancer xenograft model in zebrafish using anmutant background exists. Herein, we developed an embryonic zebrafish xenograft model using epithelial (Hep3B) and mesenchymal (SKHep1) liver cancer cell lines in wild-type andsibling ...
5A). This positive correlation was also validated in the Cancer Cell Line Encyclopedia (CCLE) database and CRC cell lines (Fig. 5B). Additionally, we analyzed chromatin immunoprecipitation sequencing (ChIP-seq) data in public datasets36 and found that the OTUD1 promoter harbored p65 binding ...
Liver Cell Carcinoma In subject area:Pharmacology, Toxicology and Pharmaceutical Science HCC, the single most common histologic type of primary epithelial liver tumor, is a malignant neoplasm of the liver showing differentiation along hepatocellular lines....
Liver cancer cell lines and animal experiments SMMC-7721 cells in Dulbecco’s Moded Eagle’s medium containing 10 % fetal bovine serum (FBS) (GIBCO BRL, Grand Island, NY, USA). The concentration of penicillin and streptomycin in the medium was 50 µg/mL, respectively; and the cells ...
In the present study, we demonstrated that the transcriptomic profiles obtained using RNA-Seq are generally invariant across the sequencing platforms (SOLiD and Illumina) and are reproducible for HepG2 cell lines across different laboratories. An evaluation of the experimental factors showed that the ...
The Journal of Liver Transplantation is a peer-reviewed gold open-access e-only publication in the field of liver transplantation publishing research articles on clinical, experimental liver transplantation, combined liver and other organ transplantation, cell and gene therapy in liver diseases. The edit...
Zebrafish lack established embryonic stem (ES) cell lines that allow for homologous recombination with targeting vectors, which is a useful technique for mice. This restricts the application of genetic recombination approaches. 3.2.1. TILLING System In 2003, Cuppen and his coworker applied the ...
Antineoplaston A10 inhibits transplanted breast cancer in athymic mice and human liver cancer cell lines.Jan 01, 1990 Click here to read the entire abstract Pubmed Data : Kurume Med J. 1990 ;37(2):97-104. PMID: 2175003 Article Published Date : Jan 01, 1990 Study Type : Transgenic ...
Colorectal cancer liver metastases (CRLM) are the primary cause of mortality in colorectal cancer (CRC) patients, highlighting the importance of understanding the underlying mechanisms. The tumor microenvironment (TME) and its interaction with tumor cell