自身免疫性肝病(autoimmune liver disease, ALD)是因体内免疫功能紊乱引起的一组特殊类型的慢性肝病,包括自身免疫性肝炎(autoimmune hepatitis ,AIH)、原发性胆汁性胆管炎(primary biliary cholangitis,PBC)、原发性硬化性胆管炎(primary sclerosing cholangitis, PSC)以及相互重叠的所谓重叠综合征(overlap syndrome)。不同...
Autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are the three major autoimmune liver diseases. So-called overlap syndromes are diseases exhibiting clinical, laboratory and or histological features of at least two of these genuine autoimmune liver ...
Autoimmune liver diseasesare a rare cause of chronic liver disease; however, they account for up to 24% of liver transplantations [1]. Autoimmune liver diseases include autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC); each of these diseases inc...
The three main categories of autoimmune liver disease are autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC); all are well-defined entities with diagnosis based upon a constellation of clinical, serologic, and liver pathology findings. Although these...
(2)thePBCexactpathogenesisremainsunclear,butthinkofbileductinjuryiscausedbytheimmunologicaldisorders,nowunderstandmaincomplex(MHC)hostsusceptibilitygenesassociatedwiththeonsetofthedisease,mainlyistheMHCⅡtypeofmolecularDR36times,DR2ishigherthanthecontrolgroup.Manyofthestudieshavebeenlinkedtoinfection,includinginfection...
Autoimmune liver disease The most commonautoimmune liver diseasesare autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). When a patient is thought to have autoimmune liver disease, an autoimmune liver disease panel is applied. Usually, the autoimmune liver disease panel includes tests for...
自身免疫性肝病 Autoimmune Liver Diseases 王贵强 北京大学第一医院 感染疾病科 北 京 大 学第一 自身免疫性肝病包括 医 院 自身免疫性肝炎(AIH) 原发性胆汁性肝硬化(PBC) 原发性硬化性胆管炎(PSC) 自身免疫性胆管炎(AIC) 自身免疫性肝病 Autoimmune Liver Diseases 王贵强 北京大学第一医院 感染疾病科 北 京...
Primary biliary cholangitis (PBC, formerly referred to asprimary biliary cirrhosis) andprimary sclerosing cholangitiscan lead to progressive scarring of the bile ducts, causing them to become narrow, which results in reduced bile flow through the liver. Eventually, damage and scarring of the liver ...
Google Share on Facebook hepatotoxicity (redirected fromToxic liver disease) Medical Related to Toxic liver disease:toxic hepatitis hep·a·to·tox·ic·i·ty (hĕp′ə-tō-tŏk-sĭs′ĭ-tē, hĭ-păt′ō-) n. 1.The quality or condition of being toxic or destructive to the live...
Note: Nonfunctional biochemical and immunologic markers of hepatic disease include those for hepatitides–HAV, HBV, HCV, HDV, HEV, and HIV, autoimmune diseases–anti-mitochondrial antibodies, PBC, malignancy–alpha-fetoprotein, relatively specific for liver cancer and metabolic diseases–ceruloplasmin in...