OBJECTIVE: To investigate effects of growth and food intake in infancy on iron status at the age of 12 months in a population with high birth weight and hi... I Thorsdottir,BS Gunnarsson,H Atladottir,... - 《European Journal of Clinical Nutrition》 被引量: 190发表: 2003年 Low prevalen...
(2) reduction and carrier-facilitated internalization of iron from transferrin without internalization of the protein moiety of transferrin, (3) electrogenic uptake of low molecular weight, non-protein bound forms of iron, and (4) uptake of heme from heme-albumin, ...
Some portion of these species may constitute the labile iron pool. Livers from mice raised on an Fe-deficient diet were highly Fe depleted; they were devoid of ferritin and contained 1/3 as much mitochondrial Fe as found in Fe-sufficient livers. In contrast, brains of the same Fe-deficient...
摘要: SUMMARYThe mean iron content of finger-nails of 113 apparently normal subjects was found to be 67.6 μg/g dry nail (±43.7). There was no age or sex variation. No relationship was found between the concentration of iron in finger-nails and that stored in the liver....
Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse Hereditary hemochromatosis (HH) is a disorder of iron metabolism in which enhanced iron absorption of dietary iron causes increased iron accumulation in the liver, heart, and pancreas. Most individuals with HH...
While this technique is reliable in low to moderate liver iron concentrations (LIC), it will be inaccurate when it is severe. We report a case with severe liver hemochromatosis and show the benefit of using an easily implemented MRI offset echo sequence to more accurately estimate LIC. After ...
Efflux of iron into the perfusate increase significantly with time and temperature. Low molecular weight chelated iron within the liver after perfusion increased from 5°88 ° 1°46 nM/gm at 37°C to 25°8 nM/gm at 42°5°C (p < 0°05). Perfusate total aldehyde levels increased from...
C. A. Rokitansky (1849) was probably the first author to refer to primary liver carcinoma as an independent disease. Until then, the problem had been to accept the existence of both primary and secondary (metastatic) liver tumours and to differentiate...
6.1.2 Iron Overload Due to the formation of free radicals, excess iron accumulation within body tissues is toxic and may result in organ damage—in particular to the liver, heart, and pancreas. It arises most commonly from either excessive intestinal absorption (e.g., hereditary hemochromatosis...
The pathogenesis of Acute-on-chronic liver failure (ACLF) involves several forms of cell death, such as pyroptosis, apoptosis, and necroptosis, which consist of PANoptosis. To explore PANoptosis as a regulated cell death pathway in ACLF. Firstly, a bioin