(2) reduction and carrier- facilitated internalization of iron from transferrin without internalization of the protein moiety of transferrin, (3) electrogenic uptake of low molecular weight, non-protein bound forms of iron, and (4) uptake of heme from heme-albumin, heme-hemopexin, or hemoglobin-...
Some portion of these species may constitute the labile iron pool. Livers from mice raised on an Fe-deficient diet were highly Fe depleted; they were devoid of ferritin and contained 1/3 as much mitochondrial Fe as found in Fe-sufficient livers. In contrast, brains of the same Fe-deficient...
Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Managanese (Mn) is an essential trace element at low concentrations, but at higher concentrations is neurotoxic. It has several chemical and biochemical pr... ACG Chua,EH...
While this technique is reliable in low to moderate liver iron concentrations (LIC), it will be inaccurate when it is severe. We report a case with severe liver hemochromatosis and show the benefit of using an easily implemented MRI offset echo sequence to more accurately estimate LIC. After ...
Efflux of iron into the perfusate increase significantly with time and temperature. Low molecular weight chelated iron within the liver after perfusion increased from 5°88 ° 1°46 nM/gm at 37°C to 25°8 nM/gm at 42°5°C (p < 0°05). Perfusate total aldehyde levels increased from...
Iron deficiency reflected in low concentrations of serum ferritin may have adverse effects on work performance even without anemia. Once anemia develops t... LH Allen,N Ahluwalia 被引量: 111发表: 1997年 The effect of calcium on iron absorption The experimental and epidemiological evidence demonstrati...
Oxidative stress and chelatable iron thus act as two hits dysfunction, and cell death. This pathway of intracellular iron translocation is a po 展开 关键词: Animals Cell Survival Hepatocytes Iron Iron Chelating Agents Iron Overload 动物 细胞存活 铁 铁超负荷 ...
The pathogenesis of Acute-on-chronic liver failure (ACLF) involves several forms of cell death, such as pyroptosis, apoptosis, and necroptosis, which consist of PANoptosis. To explore PANoptosis as a regulated cell death pathway in ACLF. Firstly, a bioin
To assess the safety and diagnostic efficacy of intravenous ferumoxides, a superparamagnetic iron oxide, for depiction of focal hepatic lesions on magnetic... PR Ros,PC Freeny,SE Harms,... - 《Radiology》 被引量: 509发表: 1995年 Regenerating nodules of liver cirrhosis: MR imaging. A large ...
PS-004-Western diet triggers a unique inflammatory phenotype of myeloid leukocytes in bone marrow and liver Jana Hundertmark, Krenkel Oliver, Trautwein Christian, Ivan G. Costa, Frank Tacke Page e7 select article PS-005-Evaluation of neuromedin-B receptor variants effect on iron metabolism and li...