2021年11月15日,北京大学药学院天然药物及仿生药物国家重点实验室刘涛研究员团队在化学生物学领域顶级期刊Nature Chemical Biology (IF=15.0)在线发表了最新研究成果"Genetic code expanded cell-based therapy for treating diabetes in mice".近年来,随着CAR-T细胞的成功上市,利用合成生物学设计的细胞治疗方式已显现出广阔的疾病治疗前景.无Journal of Chinese...
不过后来David Liu实验室采用定向进化的方法,于2020年发表了新型的PAM,可以扩展到NR,R为G或者A。今天David Liu实验室在Nature上发表的这篇论文里面用的就是 ABE8e + NRCH PAM(R为A或G,H为A或C或T)。 但是看完了这篇论文,我的心情其实是喜忧参半。先来说说好的部分,那就是ABE8e + NRCH PAM(目标的PA...
Since the new health care reform, China’s health care system has become increasingly mature and perfect, and the health awareness and needs of residents have also increased, which has raised higher r...
2021年10月4日,David Liu 实验室又在 Nature Biotechnology 杂志上发表文章公布了新一代 Prime Editor 的具体改进的细节的前半部分。后半部分将在另一篇文章上再公布。 David Liu 研究小组发现原先 PE 系统的 pegRNA 的 3' 端,因为没有像 5' 端那边一样被 Cas 蛋白给保护起来,很容易被细胞内的 exonucleases...
Corpus-assisted translation teaching: Issues and challenges. Kanglong Liu. Singapore: Springer Nature Singapore Private Limited, 2020. 168 pp., EUR85.59 (e-book)doi:10.1111/ijal.12354Jianwen LiuHong Kong Shue Yan University Hong Kong ChinaJohn Wiley & Sons, Ltd...
The Nature of Menghai, PUBLISHED BY WANG SHUYA PHOTOGRAPHS BY LIU HUAJIE NOVEMBER 5, 2021 H13Shuya WangHuajie Liu
Workplace ostracism: Its nature, antecedents, and consequences. C. Liu and J. Ma (Eds.). Cham, Springer Nature, 2021, 373 pages, $84.99 paperbackWORK environmentBUSINESS successBUSINESSPEOPLEFUNCTIONAL magnetic resonance imagingI read this book with great enthusiasm. I most ...
Since the new health care reform, China’s health care system has become increasingly mature and perfect, and the health awareness and needs of residents have also increased, which has raised higher r...
Since the new health care reform, China’s health care system has become increasingly mature and perfect, and the health awareness and needs of residents have also increased, which has raised higher r...